SALL2 and CEP76

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SALL2	CEP76
Description		spalt like transcription factor 2	centrosomal protein 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Eye Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II System Development	Regulation Of Centriole Replication
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Fruit consumption ( 32066663) Response to Homoharringtonine (cytotoxicity) ( 25628645) Tuberculosis ( 30713548)
Interacting Genes		8 interacting genes: ADAMTSL4 CEP76 CUL4A CUL4B DDB1 EWSR1 RBBP7 ZMIZ2	105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIRSR COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HACL2 HSF2 HSPB7 IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85
Entrez ID		6297	79959
HPRD ID		03743	12694
Ensembl ID		ENSG00000165821	ENSG00000101624
Uniprot IDs		B4DK65 E7EW59 F5H433 Q9Y467	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex Base-excision Repair, AP Site Formation Via Deaminated Base Removal Cul4B-RING E3 Ubiquitin Ligase Complex Ubiquitin Ligase Complex Scaffold Activity Cellular Response To UV UV-damage Excision Repair Cellular Response To Light Stimulus Cullin-RING Ubiquitin Ligase Complex Base-excision Repair, AP Site Formation Response To UV Cellular Response To Radiation Positive Regulation Of Protein Catabolic Process Protein Modification By Small Protein Conjugation DNA Metabolic Process Regulation Of Cell Cycle Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Type I Interferon-mediated Signaling Pathway Post-translational Protein Modification Response To Light Stimulus Positive Regulation Of Cell Cycle G1/S Phase Transition Damaged DNA Binding Regulation Of Mitotic Cell Cycle Phase Transition Interferon-mediated Signaling Pathway Pigment Cell Development Regulation Of Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Cycle G1/S Phase Transition Response To Radiation Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Proteasomal Protein Catabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Ribosome Biogenesis DNA Repair Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Mitotic Cell Cycle Phase Transition Protein Catabolic Process Protein Ubiquitination Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Nucleoplasm WD40-repeat Domain Binding Cellular Heat Acclimation	Protein Binding Nucleus
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