S100B and DNAJC30

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		S100B	DNAJC30
Description		S100 calcium binding protein B	DnaJ heat shock protein family (Hsp40) member C30
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cilium Microtubule Cytoskeleton Ciliary Basal Body Neuronal Cell Body Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Signaling Receptor Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Metal Ion Binding Tau Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Protein Binding
	Biological Process	Cell Adhesion Axonogenesis Central Nervous System Development Learning Or Memory Memory Positive Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Myelination Positive Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Response To Ethanol Positive Regulation Of Neuron Differentiation Regulation Of Neuronal Synaptic Plasticity Astrocyte Differentiation Positive Regulation Of Synaptic Transmission Response To Glucocorticoid Response To Methylmercury Long-term Synaptic Potentiation Cellular Response To Hypoxia Response To Anesthetic Sympathetic Neuron Projection Extension Neuron Projection Extension Adaptive Thermogenesis Negative Regulation Of Skeletal Muscle Cell Differentiation	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Nuclear signaling by ERBB4 TAK1-dependent IKK and NF-kappa-B activation Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Olopatadine Calcium N-Formylmethionine Arundic acid (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Cutaneous leishmaniasis ( 32830257) Lymphocyte count ( 22286170)	Malaria ( 31844061)
Interacting Genes		49 interacting genes: ADTRP AGER AGTRAP AHNAK ANXA6 APOE BCL2L2 CACYBP CALM1 CAPZA1 CEP20 CT45A5 DES DNAJC30 FBXO7 FBXW5 GFAP GUCY2D IFNB1 IL11 IMP4 IMPA1 IQGAP1 LDAF1 LNX1 MAL2 MAPT MDM2 MDM4 NDRG1 NKAPD1 PGM1 RABAC1 S100A1 S100A11 S100A2 S100A4 S100A6 S100A9 S100P S100Z SDCBP SPG21 STK38 SUGT1 TMEM239 TNIP1 TP53 VAV1	30 interacting genes: AQP6 BEST2 CALN1 CREB3 EBP EXOSC6 FAM209A FATE1 FBXO7 GPX8 JAGN1 KASH5 LMNA LRRC25 MGST2 MRM1 MSMO1 OPRL1 PEX12 REEP4 RNF170 S100B SIGLEC12 SLC10A4 SLC35H1 SLC51A SLC71A2 TMEM31 TMEM52B TMEM86B
Entrez ID		6285	84277
HPRD ID		01505	10303
Ensembl ID		ENSG00000160307	ENSG00000176410
Uniprot IDs		A0A0S2Z4C5 P04271	B3KSU4 Q96LL9
PDB IDs		1MQ1 1UWO 2H61 2M49 2PRU 3CZT 3D0Y 3D10 3HCM 4XYN 5CSF 5CSI 5CSJ 5CSN 5D7F	2YUA
Enriched GO Terms of Interacting Partners?		S100 Protein Binding Calcium-dependent Protein Binding Identical Protein Binding Calcium Ion Binding DNA Damage Response, Signal Transduction By P53 Class Mediator Astrocyte Development Cellular Response To Actinomycin D Transition Metal Ion Binding Cytoplasm Response To Actinomycin D Disordered Domain Specific Binding Protein Binding Cellular Response To UV-C Signal Transduction In Response To DNA Damage Cell Activation Regulation Of Intracellular Signal Transduction Endothelial Cell Migration Extracellular Exosome Protein Homodimerization Activity Negative Regulation Of Cellular Component Organization Response To Hypoxia Leukocyte Activation Signal Transduction By P53 Class Mediator Lipoprotein Particle Binding Response To Decreased Oxygen Levels Cadherin Binding Atrial Septum Development Regulation Of Synaptic Plasticity Signal Transduction Regulation Of DNA Replication Response To Metal Ion Cellular Response To Antibiotic Response To Oxygen Levels Negative Regulation Of Long-term Synaptic Potentiation RAGE Receptor Binding Extracellular Region Cellular Response To Hypoxia Cytosol Response To UV-C Regulation Of Long-term Synaptic Depression Regulation Of Blood Circulation Glial Cell Development Regulation Of Voltage-gated Calcium Channel Activity Cellular Response To Decreased Oxygen Levels Transcription Repressor Complex SCF Ubiquitin Ligase Complex	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum
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