S100A11 and NCL

Number of citations of the paper that reports this interaction (PMID 14623863)
18

Data Source:
HPRD (in vitro, in vivo)

		S100A11	NCL
Gene Name		S100 calcium binding protein A11	nucleolin
Image
Gene Ontology Annotations	Cellular Component	Ruffle Extracellular Space Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cell Cortex Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Proliferation	Angiogenesis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		4 interactors: ACTB ANXA1 NCL S100B	48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		6282	4691
HPRD ID		04385	01245
Ensembl ID		ENSG00000163191
Uniprot IDs		P31949	B3KM80 P19338 Q9BQ02
PDB IDs		1V4Z 1V50 2LUC	2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Neutrophil Clearance Response To Glucocorticoid Response To Corticosteroid DNA Rewinding Positive Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Negative Regulation Of Phospholipase A2 Activity Gliogenesis Negative Regulation Of Skeletal Muscle Cell Differentiation Negative Regulation Of Interleukin-8 Secretion Defense Response Prolactin Secretion Positive Regulation Of Prostaglandin Biosynthetic Process System Development Negative Regulation Of Phospholipase Activity Homotypic Cell-cell Adhesion Neurogenesis Positive Regulation Of Myeloid Cell Apoptotic Process Response To Methylmercury Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Phospholipase A2 Activity Anatomical Structure Development DNA Strand Renaturation Arachidonic Acid Secretion Positive Regulation Of Fatty Acid Biosynthetic Process Response To Steroid Hormone Negative Regulation Of Interleukin-8 Production Regulation Of Interleukin-8 Secretion Neutrophil Homeostasis Hepatocyte Differentiation Immune System Process Single Organismal Cell-cell Adhesion Axonogenesis Developmental Process Regulation Of Skeletal Muscle Cell Differentiation Regulation Of Transcription From RNA Polymerase I Promoter Axon Development Negative Regulation Of Lipase Activity Nervous System Development Negative Regulation Of Skeletal Muscle Tissue Development Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Vesicle Fusion Positive Regulation Of Programmed Cell Death Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Death Anatomical Structure Morphogenesis Positive Regulation Of Cell Cycle G1/S Phase Transition Neuron Projection Morphogenesis	Chromosome Organization DNA Conformation Change Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Chromatin Organization Response To Stimulus Nucleobase-containing Compound Metabolic Process Cellular Response To Stress DNA Packaging Cellular Response To Stimulus Developmental Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Gene Expression Regulation Of Apoptotic Process Chromatin Assembly Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Cell Death Chromatin Assembly Or Disassembly Response To Stress Mitotic Cell Cycle Checkpoint Regulation Of Cell Proliferation DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Aging Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process RNA Biosynthetic Process Cellular Senescence Double-strand Break Repair Protein Complex Assembly DNA Damage Checkpoint Cell Cycle Process Regulation Of RNA Metabolic Process Mitotic Cell Cycle Process
Tagcloud ?		a2 abstract accumulates annexin annexins ca2 constant cytoskeleton damaged depending ef entry environment harsh imposed initiates injured metastatic motility organelles partner pm pmr repair respond stresses stroma	affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Difference) ?		a2 abstract accumulates annexin annexins ca2 constant cytoskeleton damaged depending ef entry environment harsh imposed initiates injured metastatic motility organelles partner pm pmr repair respond stresses stroma	affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Intersection) ?