S100A11

Name	S100 calcium binding protein A11
Structure
Interactors	10 interactors: ACTB ANXA1 CEBPA CEP20 ERBB2 ERBB4 NCL NTAQ1 S100B TNF
GO Annotations	Cellular Component	Ruffle Extracellular Region Extracellular Space Nucleus Cytoplasm Adherens Junction Secretory Granule Lumen Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity S100 Protein Binding Metal Ion Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Signal Transduction Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Population Proliferation Cell-cell Adhesion
Pathways	Neutrophil degranulation
Drugs	Phosphonothreonine
GWAS	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 ) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 ) Allergic disease (asthma, hay fever or eczema) ( 29785011 ) Asthma ( 30929738 31619474 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Male-pattern baldness ( 28196072 )
Entrez ID	6282
HPRD ID	04385
Ensembl ID	ENSG00000163191
Uniprot IDs	P31949 V9HWH9
PDB IDs	1V4Z 1V50 2LUC
GO Terms Enriched among Interactors ?	Negative Regulation Of Cell Differentiation Response To Glucocorticoid Response To Corticosteroid Regulation Of Multicellular Organismal Development Regulation Of Hemopoiesis Cellular Response To Epidermal Growth Factor Stimulus ERBB2-ERBB4 Signaling Pathway Response To Epidermal Growth Factor Positive Regulation Of Cell Population Proliferation Negative Regulation Of Developmental Process Response To Steroid Hormone Regulation Of Cell Population Proliferation Identical Protein Binding ERBB4 Signaling Pathway Negative Regulation Of Cell Development Protein Localization To Cell Junction Cellular Response To Growth Factor Stimulus Regulation Of Cell Activation Response To Growth Factor Positive Regulation Of Developmental Process Negative Regulation Of Hemopoiesis Regulation Of Apoptotic Process Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Positive Regulation Of Cell Activation Regeneration Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Localization To Cell Surface Regulation Of Programmed Cell Death Positive Regulation Of Cell Differentiation ERBB2 Signaling Pathway Regulation Of Cell Differentiation Regulation Of Developmental Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Phagocytic Cup Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Positive Regulation Of Transcription By RNA Polymerase I Regulation Of T Cell Differentiation Protein Localization To Postsynaptic Membrane Positive Regulation Of Biosynthetic Process Positive Regulation Of Leukocyte Differentiation Negative Regulation Of Immune System Process Protein Localization To Postsynapse Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of MAP Kinase Activity Positive Regulation Of RNA Metabolic Process