ARL13B and YIPF6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARL13B	YIPF6
Description		ARF like GTPase 13B	Yip1 domain family member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Membrane Motile Cilium Ciliary Basal Body Cell Projection Intercellular Bridge Ciliary Membrane Non-motile Cilium	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Trans-Golgi Network Endomembrane System Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding Identical Protein Binding
	Biological Process	Heart Looping Smoothened Signaling Pathway Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Neural Tube Patterning Interneuron Migration From The Subpallium To The Cortex Formation Of Radial Glial Scaffolds Cilium Assembly Left/right Axis Specification Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intestinal Epithelial Cell Development
Pathways		ARL13B-mediated ciliary trafficking of INPP5E RHOQ GTPase cycle RHOJ GTPase cycle Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Golgi Associated Vesicle Biogenesis
Drugs
Diseases		Joubert syndrome
GWAS			Male-pattern baldness ( 28196072)
Interacting Genes		146 interacting genes: ACSF2 AIG1 ALG3 ANKRD46 AOC3 AQP10 ARLN B4GALNT2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C1GALT1 C2CD2L CCDC167 CCL4 CCL4L2 CD151 CD302 CD53 CDIPT CFHR5 CLDN4 CLDN8 CLEC4G CLEC7A CLN6 CMTM3 CMTM7 COL8A2 CSGALNACT2 CTSA CXCL16 CYB561D2 EBP EMP1 ENTPD3 ERG28 FAXDC2 FDFT1 FKBP8 FUNDC2 FXYD6 GAD2 GIMAP1 GIMAP5 GJB2 GOSR2 GPR37L1 HMOX1 HMOX2 HOMER3 ICMT IGFBP5 INSIG2 ITGAM JAGN1 KCNJ2 KLRG1 LEPROTL1 LHFPL5 LPAR3 MAL2 MALL MMD MOSPD3 MUCL1 MYADML2 NAT8 NINJ2 NKG7 NRM NUCB2 ORMDL1 ORMDL3 PAEP PDZK1IP1 PGAP2 PKNOX1 PLN PLP1 PLP2 PLPP4 PLPPR2 PMP22 PNLIPRP1 PRB1 PTPN9 RTP2 RUSF1 S100A2 SACM1L SEMA4G SLC13A3 SLC2A5 SLC35A1 SLC35B1 SLC38A7 SLC39A2 SMAGP SMCO4 SPN STRIT1 STX1A STX7 STX8 TECR TEX264 TFRC THSD7A THSD7B TM6SF2 TMEM11 TMEM120B TMEM121 TMEM128 TMEM14B TMEM14C TMEM187 TMEM190 TMEM218 TMEM229B TMEM254 TMEM43 TMEM54 TMEM60 TMEM65 TMEM79 TMEM86B TMEM97 TMUB2 TNFRSF10C TNMD TRARG1 TSPO2 UBE2I VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VSTM1 WFDC2 YIPF6 ZDHHC15	93 interacting genes: APOL2 AQP2 AQP6 ARL13B ATP6V0E1 CD79A CGRRF1 CISD2 CLN8 CNR2 CPLX4 CRB3 CREB3L1 CREB3L3 CXorf66 CYSLTR2 EBP EFNA5 ELOVL4 ERGIC3 F2RL1 FAM209A FCER1G FFAR2 FKBP7 GJA5 GJA8 GJB1 GPR101 GPR152 GPR42 GPX8 HSD17B11 IL10RA IL1RL1 IL27RA JKAMP KCNJ6 KCNK5 LMNA LRRC25 LRRC3B LRRC4C LY6G6C LYVE1 MMD MS4A3 MTIF3 MUC1 NDUFAF1 ODF4 PDZK1IP1 PSCA RAET1L REEP4 RETREG3 RHCG RNF185 SCN3B SLC10A1 SLC10A6 SLC12A7 SLC17A8 SLC18A1 SLC30A4 SLC30A8 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SLC61A1 SLC71A2 SLC7A14 SLC7A8 SSMEM1 STOM TCTA THAP4 TMEM106C TMEM11 TMEM130 TMEM14B TMEM237 TMEM31 TMEM52B TMEM71 TMX2 TRARG1 TRHR TVP23B ULBP2 YIPF1 YIPF2
Entrez ID		200894	286451
HPRD ID		12334	06639
Ensembl ID		ENSG00000169379	ENSG00000181704
Uniprot IDs		A0A7P0T892 A0A7P0T933 A0A7P0Z473 Q3SXY8	Q96EC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Complex Protein Binding SNAP Receptor Activity SNARE Complex Assembly Plasma Membrane Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Establishment Of Protein Localization To Plasma Membrane Endomembrane System Chloride Channel Inhibitor Activity Sterol Biosynthetic Process Bleb Assembly Heme Oxidation Heme Oxygenase (decyclizing) Activity Structural Constituent Of Myelin Sheath Membrane Fusion Specific Granule Membrane Establishment Of Protein Localization To Membrane Vesicle Organization Membrane Organization Myelination Axon Ensheathment Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Heme Metabolic Process SNARE Binding Identical Protein Binding Transport Vesicle Golgi To Plasma Membrane Protein Transport Lipid Metabolic Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Porphyrin-containing Compound Metabolic Process Lipid Homeostasis Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process	Membrane Transmembrane Transport Plasma Membrane Protein Binding Endoplasmic Reticulum Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Monoatomic Cation Transport Zinc Ion Transmembrane Transport Zinc Ion Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Inorganic Ion Transmembrane Transport Regulation Of Renin Secretion Into Blood Stream Amino Acid Transmembrane Transport Connexin Complex Import Across Plasma Membrane Gap Junction Channel Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Positive Regulation Of Acute Inflammatory Response Gap Junction Transmembrane Transporter Activity SA Node Cell Action Potential Side Of Membrane Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Monoatomic Cation Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Renal Water Transport Monoatomic Ion Transmembrane Transport Gap Junction Assembly Golgi Trans Cisterna Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Ammonium Channel Activity G Protein-coupled Receptor Activity Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Golgi Medial Cisterna
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