CLIP1 and MAPRE1

Number of citations of the paper that reports this interaction (PMID 16455083)
13

Data Source:
BioGRID (pull down)

		CLIP1	MAPRE1
Gene Name		CAP-GLY domain containing linker protein 1	microtubule-associated protein, RP/EB family, member 1
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Ruffle Cytoplasm Endosome Centrosome Cytosol Microtubule Cytoplasmic Microtubule Intermediate Filament Microtubule Cytoskeleton Cytoplasmic Vesicle Membrane Microtubule Plus-end Macropinosome	Cytoplasm Golgi Apparatus Centrosome Spindle Cytosol Microtubule Cytoplasmic Microtubule Cortical Microtubule Cytoskeleton Cell Projection Membrane Microtubule Plus-end
	Molecular Function	Nucleic Acid Binding Protein Binding Microtubule Binding Zinc Ion Binding Tubulin Binding Protein Homodimerization Activity Metal Ion Binding Microtubule Plus-end Binding	Protein Binding Protein C-terminus Binding Poly(A) RNA Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Cell Cycle Microtubule Bundle Formation Mitotic Nuclear Division Positive Regulation Of Microtubule Polymerization Protein Transport Into Plasma Membrane Raft	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Cell Proliferation Negative Regulation Of Microtubule Polymerization Protein Localization To Microtubule Cell Division Positive Regulation Of Microtubule Plus-end Binding
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CALM1 CLASP2 DCTN1 IQGAP1 MAPRE1 MAPRE2 MTOR PAFAH1B1 TUBA1A TUBB	40 interactors: ABCB1 APC APC2 APP AURKB BCL3 CDK5RAP2 CLASP1 CLASP2 CLIP1 COPS5 COPS8 CSN3 CYLD DCTN1 HSPA1A IKBKG KAT2B KAT5 KIF2C LMO2 LRP1 MACF1 MAPRE2 MAPRE3 NAV1 NUPR1 PDE4DIP PIK3R4 POLE2 PQBP1 PSMA1 SPDYE2 STK11 TERF1 TRAF2 TRIO TROAP TUBA1A TUBB
Entrez ID		6249	22919
HPRD ID		01568	04379
Ensembl ID		ENSG00000130779	ENSG00000101367
Uniprot IDs		B3KXA5 P30622	B4DM33 Q15691
PDB IDs		2CP5 2CP6 2E3H 2E3I 2E4H 2HQH 2QK0 3E2U 3RDV	1PA7 1TXQ 1UEG 1VKA 1WU9 1YIB 1YIG 2HKQ 2HL3 2HL5 2QJZ 2R8U 3GJO 3TQ7
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Division Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Cytoskeleton-dependent Intracellular Transport Cell Cycle Organelle Organization Microtubule-based Process Cellular Localization Protein Polymerization Microtubule Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Cellular Protein Complex Assembly Positive Regulation Of Protein Modification Process Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Carbohydrate Utilization Cellular Response To Organic Substance Regulation Of Protein Phosphorylation Establishment Of Localization In Cell Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Cytoskeleton Organization Cell Projection Organization Positive Regulation Of Kinase Activity Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Immune System Process Response To Calcium Ion Positive Regulation Of Protein Metabolic Process Regulation Of Ras GTPase Activity Microtubule-based Transport Positive Regulation Of Microtubule Plus-end Binding Establishment Of Centrosome Localization Regulation Of Dephosphorylation	Cell Cycle Process Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Cycle G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Microtubule-based Process Response To Stimulus Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Complex Assembly Regulation Of Cytoskeleton Organization Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Microtubule Depolymerization Regulation Of Chromosome Segregation Cullin Deneddylation Cellular Localization Regulation Of Wnt Signaling Pathway Establishment Or Maintenance Of Cell Polarity Response To Radiation Protein Deneddylation Negative Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Spindle Checkpoint Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Microtubule Bundle Formation Response To Light Stimulus Cellular Protein Complex Assembly Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Positive Regulation Of Transferase Activity
Tagcloud ?		clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm microtubule microtubules movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips tracking vertebrate xenopus	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		clasp1 cranial cytoskeleton ectoderm ectodermal embryogenesis gastrulation glued hemisphere involuting laevis lis1 maternally mesoderm movements nerves neurogenesis p150 persists platforms progresses stim1 tip tips vertebrate xenopus	akap450 akap9 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby trafficking tubulin variant
Tagcloud (Intersection) ?		microtubule microtubules tracking