ENOPH1 and ZNF280A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ENOPH1	ZNF280A
Description		enolase-phosphatase 1	zinc finger protein 280A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Acireductone Synthase Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Methionine salvage pathway
Drugs		2-OXOHEPTYLPHOSPHONIC ACID
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: ERBB3 RAB10 RPS27 TMEM132D TSC22D2 ZNF280A	8 interacting genes: CABP5 CALM1 CALM2 CALM3 EIF1AD ENOPH1 KDM1A PDE4C
Entrez ID		58478	129025
HPRD ID		17467	18129
Ensembl ID		ENSG00000145293	ENSG00000169548
Uniprot IDs		D6RA00 Q9UHY7	A0A0G2JN84 P59817
PDB IDs		1YNS 1ZS9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Negative Regulation Of Intralumenal Vesicle Formation GDP Binding Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Secretory Granule Membrane Establishment Of Protein Localization To Plasma Membrane Synaptic Vesicle Recycling Via Endosome Phagocytic Vesicle Membrane G Protein Activity Neuregulin Receptor Activity Vesicle-mediated Transport To The Plasma Membrane Lipophagy Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Negative Regulation Of Secretion ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Protein To Membrane Docking Negative Regulation Of Exosomal Secretion Regulation Of Endosome Organization Protein Localization To Plasma Membrane Alveolar Lamellar Body Insulin-responsive Compartment Schwann Cell Differentiation Phagosome Acidification Establishment Of Protein Localization To Membrane Presynaptic Endosome ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Localization To Cell Periphery Secretory Vesicle Retromer Complex Binding Negative Regulation Of Motor Neuron Apoptotic Process Phagosome Maturation Endosomal Transport	Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Calcium Channel Regulator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Calcium Channel Complex Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Sperm Midpiece Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcomere Cell Cycle G2/M Phase Transition Neural Nucleus Development Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Voltage-gated Calcium Channel Activity Calcium-dependent Protein Binding Voltage-gated Potassium Channel Complex Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Cytokinesis Vesicle-mediated Transport In Synapse Regulation Of Calcium-mediated Signaling Regulation Of Striated Muscle Contraction
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