ENOPH1 and RPS27

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ENOPH1	RPS27
Description		enolase-phosphatase 1	ribosomal protein S27
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Presynapse Glutamatergic Synapse GABA-ergic Synapse Ribonucleoprotein Complex
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Acireductone Synthase Activity Metal Ion Binding	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine	Ribosomal Small Subunit Assembly Cytoplasmic Translation RRNA Processing Translation Ribosomal Small Subunit Biogenesis
Pathways		Methionine salvage pathway	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs		2-OXOHEPTYLPHOSPHONIC ACID
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: ERBB3 RAB10 RPS27 TMEM132D TSC22D2 ZNF280A	16 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 MRPS18C NACAD NSG2 PPBP PSME3 PTEN RTN4 SKIL TOM1 WDCP
Entrez ID		58478	6232
HPRD ID		17467	04744
Ensembl ID		ENSG00000145293	ENSG00000177954
Uniprot IDs		D6RA00 Q9UHY7	P42677
PDB IDs		1YNS 1ZS9	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8RG0 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Negative Regulation Of Intralumenal Vesicle Formation GDP Binding Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Secretory Granule Membrane Establishment Of Protein Localization To Plasma Membrane Synaptic Vesicle Recycling Via Endosome Phagocytic Vesicle Membrane G Protein Activity Neuregulin Receptor Activity Vesicle-mediated Transport To The Plasma Membrane Lipophagy Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Negative Regulation Of Secretion ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Protein To Membrane Docking Negative Regulation Of Exosomal Secretion Regulation Of Endosome Organization Protein Localization To Plasma Membrane Alveolar Lamellar Body Insulin-responsive Compartment Schwann Cell Differentiation Phagosome Acidification Establishment Of Protein Localization To Membrane Presynaptic Endosome ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Localization To Cell Periphery Secretory Vesicle Retromer Complex Binding Negative Regulation Of Motor Neuron Apoptotic Process Phagosome Maturation Endosomal Transport	Platelet Alpha Granule Lumen Cell Junction Pseudopodium
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