ENOPH1 and TMEM132D

Number of citations of the paper that reports this interaction (PubMedID 33726789)
50

Data Source:
BioGRID (two hybrid)

		ENOPH1	TMEM132D
Description		enolase-phosphatase 1	transmembrane protein 132D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Membrane
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Acireductone Synthase Activity Metal Ion Binding	Protein Binding
	Biological Process	Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine
Pathways		Methionine salvage pathway
Drugs		2-OXOHEPTYLPHOSPHONIC ACID
Diseases
GWAS			Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anxiety disorder ( 25390645) Asthma ( 29273806) Blood protein levels ( 30072576) Body fat mass ( 28552196) Cognitive decline rate in late mild cognitive impairment ( 26252872) Heart rate ( 23534349) Initial pursuit acceleration ( 29064472) Male-pattern baldness ( 27182965) Mosquito bite size ( 28199695) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Retinal venular tortuosity ( 31597446) Schizophrenia (inflammation and infection response interaction) ( 25781172) Sleep (1/2-day periodicity) ( 33075057) Triglyceride levels ( 34074324) Trunk fat mass ( 28552196) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		6 interacting genes: ERBB3 RAB10 RPS27 TMEM132D TSC22D2 ZNF280A	70 interacting genes: ANKRD31 ANKRD36 ARL3 ATP1B1 ATP7A BNIP3L CADPS2 CCDC85A CD59 CMPK1 CNGB3 CNTN1 COMMD1 COX11 CPD EFEMP1 ENOPH1 FAM106A FMO2 GFM2 H3C1 HDAC2 HEBP2 HNRNPUL1 HOXA9 IDI2-AS1 IL13RA1 LNX1 MIR181A1HG MME NAMPT NCKAP1 NDUFS5 NPAS3 PAIP1 PCCA PCLO PGM1 PLSCR2 PNISR PRMT3 PRPF40A PTPN2 PTPRD RAB6A RCBTB2 RNF2 SAMD12 SDHB SEC22B SHLD2 SLC35E2A SRSF5 STK39 SVIL TCF12 TMED5 TMED7-TICAM2 TNFAIP8 TOB2 TPST1 TRAPPC11 TRAPPC8 TUBGCP5 UBA5 UMOD USP32P2 VPS13C ZBTB20 ZNF302
Entrez ID		58478	121256
HPRD ID		17467	13906
Ensembl ID		ENSG00000145293	ENSG00000151952
Uniprot IDs		D6RA00 Q9UHY7	Q14C87
PDB IDs		1YNS 1ZS9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Negative Regulation Of Intralumenal Vesicle Formation GDP Binding Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Secretory Granule Membrane Establishment Of Protein Localization To Plasma Membrane Synaptic Vesicle Recycling Via Endosome Phagocytic Vesicle Membrane G Protein Activity Neuregulin Receptor Activity Vesicle-mediated Transport To The Plasma Membrane Lipophagy Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Negative Regulation Of Secretion ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Protein To Membrane Docking Negative Regulation Of Exosomal Secretion Regulation Of Endosome Organization Protein Localization To Plasma Membrane Alveolar Lamellar Body Insulin-responsive Compartment Schwann Cell Differentiation Phagosome Acidification Establishment Of Protein Localization To Membrane Presynaptic Endosome ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Localization To Cell Periphery Secretory Vesicle Retromer Complex Binding Negative Regulation Of Motor Neuron Apoptotic Process Phagosome Maturation Endosomal Transport	Golgi Vesicle Transport Protein Transport Into Plasma Membrane Raft Purine Nucleotide Metabolic Process Nucleotide Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process ATP Metabolic Process Nucleoside Phosphate Metabolic Process Protein Transport Into Membrane Raft Positive Regulation Of Potassium Ion Import Across Plasma Membrane Purine Ribonucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Protein Localization To Plasma Membrane Raft Purine-containing Compound Metabolic Process Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Import Positive Regulation Of Sodium Ion Transport
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