RPS26 and TSR2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		RPS26	TSR2
Gene Name		ribosomal protein S26	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus
	Molecular Function	MRNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Negative Regulation Of RNA Splicing Cellular Protein Metabolic Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Psoriasis ( 20953189) Vitiligo ( 22951725)
Protein-Protein Interactions		3 interactors: APP NDRG1 TSR2	5 interactors: GABARAPL2 KIFC3 PIAS2 RPS26 ZBTB9
Entrez ID		6231	90121
HPRD ID		04743	06493
Ensembl ID		ENSG00000197728	ENSG00000158526
Uniprot IDs		P62854	Q969E8
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Positive Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Spindle Checkpoint Axon Choice Point Recognition Neuron Remodeling Positive Regulation Of Cell Cycle Checkpoint Regulation Of Cell Cycle Process Cellular Copper Ion Homeostasis Peripheral Nervous System Myelin Maintenance Cell Activation Copper Ion Homeostasis Suckling Behavior Regulation Of Spindle Checkpoint Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Myelin Maintenance Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Maturation Of SSU-rRNA Mast Cell Activation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Cycle RNA Polyadenylation Neuron Recognition Regulation Of Cell Cycle Checkpoint Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ribosomal Small Subunit Biogenesis Myelination In Peripheral Nervous System Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Schwann Cell Development Regulation Of Cell Cycle G2/M Phase Transition Response To Abiotic Stimulus Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Schwann Cell Differentiation Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway
Tagcloud ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps10 rps17 rps19 rps24 supports variations
Tagcloud (Difference) ?		26t 2a aberrations anemia blackfan cgh congenital copy dba deletions diamond fourfold haploinsufficiency heterozygous hyperactivation hypoproliferative korean malformations predisposition reductions rpl11 rpl35a rpl5 rps10 rps17 rps19 rps24 supports variations
Tagcloud (Intersection) ?