RPS3A and VDAC2

Number of citations of the paper that reports this interaction (PMID 15047060)
3

Data Source:
HPRD (in vitro)

		RPS3A	VDAC2
Gene Name		ribosomal protein S3A	voltage-dependent anion channel 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Nucleoid Pore Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding Voltage-gated Anion Channel Activity Porin Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cell Differentiation Negative Regulation Of Apoptotic Process Cellular Protein Metabolic Process	Anion Transport Negative Regulation Of Protein Polymerization Regulation Of Anion Transport Transmembrane Transport Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)
Protein-Protein Interactions		15 interactors: ATF7IP C11orf49 CCDC50 CHN1 DDIT3 EDEM2 FANCC HGS HSP90AA1 NEDD4 PARP1 SAP18 SOD2 TOE1 VDAC2	8 interactors: ADRB2 APP BAK1 CYCS ECT2 HK1 NEDD4L RPS3A
Entrez ID		6189	7417
HPRD ID		01606	01904
Ensembl ID		ENSG00000145425	ENSG00000165637
Uniprot IDs		B7Z3M5 P61247	P45880
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Cellular Response To Superoxide Response To Superoxide Response To Oxygen Radical Cellular Response To Reactive Oxygen Species Protein Targeting To Lysosome Reactive Oxygen Species Metabolic Process Protein Localization To Lysosome Removal Of Superoxide Radicals Response To Unfolded Protein Cellular Response To Stress Positive Regulation Of Metabolic Process Protein Targeting To Vacuole Response To Inorganic Substance Establishment Of Protein Localization To Vacuole Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Signal Transduction Negative Regulation Of RNA Biosynthetic Process Superoxide Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Lysosomal Transport Regulation Of Signaling Negative Regulation Of Gene Expression Cytoplasmic Transport Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Stress Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Response To DNA Damage Stimulus Establishment Of Protein Localization To Organelle Vacuolar Transport Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Neuron Development	Positive Regulation Of Protein Metabolic Process Transport Response To Oxidative Stress Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Regulation Of Protein Metabolic Process Cellular Chemical Homeostasis Negative Regulation Of Systemic Arterial Blood Pressure Response To Reactive Oxygen Species Homeostatic Process Cellular Homeostasis Positive Regulation Of Catalytic Activity Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Binding Positive Regulation Of Proteolysis Chemical Homeostasis Negative Regulation Of Blood Pressure Apoptotic Signaling Pathway Apoptotic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Programmed Cell Death Regulation Of Sodium Ion Transport Response To Stress Positive Regulation Of Hydrolase Activity Regulation Of Endopeptidase Activity Cell Death Death Regulation Of Protein Phosphorylation Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Metal Ion Homeostasis Response To Inorganic Substance Regulation Of Catalytic Activity Activation Of Cysteine-type Endopeptidase Activity Regulation Of Systemic Arterial Blood Pressure Regulation Of Multicellular Organism Growth Regulation Of Phosphorylation Zymogen Activation Positive Regulation Of Cellular Metabolic Process Tissue Remodeling Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis
Tagcloud ?			adrenals carbohydrate cholesterol continues enter gonads hormonal hormones initiating interact interacts location mam mature mitochondria mitochondrial ovaries pregnenolone processed processing prolactin reproduction star steroid steroidogenesis steroidogenic terminus tom22 transports
Tagcloud (Difference) ?			adrenals carbohydrate cholesterol continues enter gonads hormonal hormones initiating interact interacts location mam mature mitochondria mitochondrial ovaries pregnenolone processed processing prolactin reproduction star steroid steroidogenesis steroidogenic terminus tom22 transports
Tagcloud (Intersection) ?