VDAC2

Description		voltage dependent anion channel 2
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GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Mitochondrion Mitochondrial Outer Membrane Membrane Mitochondrial Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Sperm Midpiece
	Molecular Function	Nucleotide Binding Voltage-gated Monoatomic Ion Channel Activity Protein Binding ATP Binding Oxysterol Binding Lipid Binding Voltage-gated Monoatomic Anion Channel Activity Porin Activity Cholesterol Binding Phospholipid Scramblase Activity Phosphatidylcholine Binding Ceramide Binding
	Biological Process	Monoatomic Ion Transport Monoatomic Anion Transport Lipid Transport Binding Of Sperm To Zona Pellucida Plasma Membrane Phospholipid Scrambling Phospholipid Translocation Transmembrane Transport Mitochondrial Outer Membrane Permeabilization Monoatomic Anion Transmembrane Transport Mitochondrial Transmembrane Transport
Pathways		PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases Mitochondrial calcium ion transport
Drugs		Aluminium monostearate PRLX 93936
Diseases
GWAS
Interacting Genes		12 interacting genes: ADRB2 APP BAK1 CFTR CYCS DUX4 DUX4L9 ECT2 HK1 NEDD4 NEDD4L RPS3A
Entrez ID		7417
HPRD ID		01904
Ensembl ID		ENSG00000165637
Uniprot IDs		A0A024QZT0 B4DKM5 P45880
PDB IDs		9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Potential Regulation Of Monoatomic Ion Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Negative Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Transport Regulation Of Sodium Ion Transport Sodium Channel Inhibitor Activity Potassium Channel Inhibitor Activity Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Transport Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Protein-folding Chaperone Binding Positive Regulation Of CAMP/PKA Signal Transduction Receptor Catabolic Process Neuronal Dense Core Vesicle Transmembrane Transporter Binding Negative Regulation Of Potassium Ion Transmembrane Transport Enzyme Binding Positive Regulation Of Protein Metabolic Process Positive Regulation Of Excitatory Postsynaptic Potential Endocytosis Ionotropic Glutamate Receptor Signaling Pathway Receptor-mediated Endocytosis Cell Junction Organization Response To Radiation Cellular Response To Radiation Negative Regulation Of Potassium Ion Transport Positive Regulation Of Macromolecule Metabolic Process Neuromuscular Junction Development Cytosol Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Intracellular Chemical Homeostasis Regulation Of Cellular Localization Positive Regulation Of Metabolic Process Regulation Of CAMP/PKA Signal Transduction Import Into Cell Positive Regulation Of Cell Communication Glutamate Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Catabolic Process Positive Regulation Of Signaling Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Mini Excitatory Postsynaptic Potential
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