RPS2 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPS2	ANXA7
Gene Name		ribosomal protein S2	annexin A7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	MRNA Binding Structural Constituent Of Ribosome Protein Binding Fibroblast Growth Factor Binding Enzyme Binding Poly(A) RNA Binding	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ANXA7 CDKN1A DNM2 FGF1 FGF3 GABARAPL2 GADD45A GRB7 GSK3B MPP3 PRMT3 SMN1 SOX5 TK1 YWHAG	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		6187	310
HPRD ID		04690	01720
Ensembl ID		ENSG00000140988	ENSG00000138279
Uniprot IDs		P15880	B2R657 P20073
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Phosphatidylinositol-mediated Signaling Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Kinase Activity Cellular Response To Heat Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Negative Regulation Of Kinase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Fc Receptor Signaling Pathway Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Cell Death Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Heat Response To Stimulus Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Kinase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Phosphorylation Regulation Of Kinase Activity Anatomical Structure Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Immune Response-regulating Signaling Pathway Response To Hormone Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Temperature Stimulus Organ Induction System Development Cellular Response To Insulin Stimulus Regulation Of Neuron Differentiation Regulation Of Catalytic Activity Cellular Response To Stimulus Cell Cycle Process Regulation Of Protein Phosphorylation Developmental Process	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?		1x10 a2ic aa2t abi analyzer bait bigdye ccdc32 gal gal4 heterotetramer lexa ligated monocyte ncbi nlm ogdh papd4 pbtm116 plasmin prey prism procathepsin ready reconstituting resultant snx17 terminator zbtb4	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?		1x10 a2ic aa2t abi analyzer bait bigdye ccdc32 gal gal4 heterotetramer lexa ligated monocyte ncbi nlm ogdh papd4 pbtm116 plasmin prey prism procathepsin ready reconstituting resultant snx17 terminator zbtb4	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?