OLIG1 and SHD

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		OLIG1	SHD
Description		oligodendrocyte transcription factor 1	Src homology 2 domain containing transforming protein D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Phosphotyrosine Residue Binding Protein Binding
	Biological Process	Sensory Organ Development Oligodendrocyte Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Axon Development
Pathways
Drugs
Diseases
GWAS			Post-bronchodilator lung function in asthma (FVC) ( 32989782)
Interacting Genes		15 interacting genes: CACNA1A DOK4 DOK5 GRB2 HSH2D MRPL12 NCK1 NUMB PSMD14 PTPN6 RASA1 SH2D1A SH2D4A SHD STAT5A	14 interacting genes: ABL1 BECN1 CAPN10 EGFR ERBB2 ERBB3 ERBB4 KRTCAP2 MET MRPS22 NCK2 OLIG1 OSBPL6 PSG11
Entrez ID		116448	56961
HPRD ID		07333	15337
Ensembl ID		ENSG00000184221	ENSG00000105251
Uniprot IDs		Q8TAK6	Q96IW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphotyrosine Residue Binding Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Lymphocyte Activation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Lymphocyte Mediated Immunity T Cell Activation Leukocyte Activation Leukocyte Mediated Immunity Enzyme-linked Receptor Protein Signaling Pathway Cell Activation Regulation Of T Cell Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cell Killing Regulation Of Lymphocyte Mediated Immunity Protein-macromolecule Adaptor Activity Negative Regulation Of Immune System Process Positive Regulation Of T Cell Activation Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Actin Filament Polymerization Innate Immune Response Positive Regulation Of Lymphocyte Activation Regulation Of MAPK Cascade Positive Regulation Of Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Leukocyte Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Immune Effector Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Ephrin Receptor Binding Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Defense Response To Other Organism Regulation Of Cell Adhesion Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of B Cell Differentiation Vesicle Membrane Regulation Of Innate Immune Response Regulation Of T Cell Proliferation Cell-cell Junction T Cell Costimulation Negative Regulation Of Immune Response Positive Regulation Of Cell Adhesion	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Protein Tyrosine Kinase Activity Basal Plasma Membrane ERBB2 Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Epidermal Growth Factor Stimulus Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Neuron Differentiation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Programmed Cell Death Receptor Complex ERBB3:ERBB2 Complex Protein Kinase Activity Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Cellular Response To Growth Factor Stimulus Negative Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Apoptotic Process Kinase Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB2-EGFR Signaling Pathway Glial Cell Development Positive Regulation Of Cell Communication Positive Regulation Of MAPK Cascade Positive Regulation Of Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Negative Regulation Of Apoptotic Process Basolateral Plasma Membrane Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cell Population Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Animal Organ Development Regulation Of Intracellular Signal Transduction Regulation Of ERK1 And ERK2 Cascade Endosome Membrane Protein Tyrosine Kinase Activator Activity Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Glial Cell Differentiation Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Signal Transduction
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