OLIG1 and DOK4

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		OLIG1	DOK4
Description		oligodendrocyte transcription factor 1	docking protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Sensory Organ Development Oligodendrocyte Development Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Axon Development	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Positive Regulation Of MAPK Cascade
Pathways			RET signaling
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: CACNA1A DOK4 DOK5 GRB2 HSH2D MRPL12 NCK1 NUMB PSMD14 PTPN6 RASA1 SH2D1A SH2D4A SHD STAT5A	21 interacting genes: CRK EGFR ERBB2 FYN IGF1R INCA1 INSR LIX1 MAPRE3 OLIG1 OPRM1 PAX8 PFDN5 PTK2 RASA1 RBP7 RET RHOU SRC STAT2 TEK
Entrez ID		116448	55715
HPRD ID		07333	16316
Ensembl ID		ENSG00000184221	ENSG00000125170
Uniprot IDs		Q8TAK6	H3BQ19 Q8TEW6
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphotyrosine Residue Binding Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Lymphocyte Activation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Lymphocyte Mediated Immunity T Cell Activation Leukocyte Activation Leukocyte Mediated Immunity Enzyme-linked Receptor Protein Signaling Pathway Cell Activation Regulation Of T Cell Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Cell Killing Regulation Of Lymphocyte Mediated Immunity Protein-macromolecule Adaptor Activity Negative Regulation Of Immune System Process Positive Regulation Of T Cell Activation Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Actin Filament Polymerization Innate Immune Response Positive Regulation Of Lymphocyte Activation Regulation Of MAPK Cascade Positive Regulation Of Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Leukocyte Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Immune Effector Process Regulation Of T Cell Activation Positive Regulation Of Cell Activation Ephrin Receptor Binding Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Defense Response To Other Organism Regulation Of Cell Adhesion Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of B Cell Differentiation Vesicle Membrane Regulation Of Innate Immune Response Regulation Of T Cell Proliferation Cell-cell Junction T Cell Costimulation Negative Regulation Of Immune Response Positive Regulation Of Cell Adhesion	Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Communication Ephrin Receptor Signaling Pathway Regulation Of Signaling Regulation Of Developmental Process Protein Kinase Activity Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Component Organization Regulation Of Signal Transduction Regulation Of Cell Morphogenesis Positive Regulation Of Intracellular Signal Transduction Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Receptor Complex Positive Regulation Of Cell Migration Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Apoptotic Process Positive Regulation Of Cell Motility Dendritic Spine Maintenance Positive Regulation Of Locomotion Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Shape Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration Epidermal Growth Factor Receptor Signaling Pathway Phosphatidylinositol 3-kinase Binding Signal Transduction Regulation Of Cell Motility Response To Growth Factor Positive Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Locomotion Regulation Of Cell-substrate Junction Organization ERBB Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cell Adhesion ERBB2 Signaling Pathway Protein Phosphorylation
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