RPLP0 and STAU1

Number of citations of the paper that reports this interaction (PMID 15121898)
40

Data Source:
HPRD (in vitro)

		RPLP0	STAU1
Gene Name		ribosomal protein, large, P0	staufen double-stranded RNA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Microtubule Associated Complex Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosome Biogenesis Cellular Protein Metabolic Process	Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CCNDBP1 CSNK2A1 ERG GAS7 KRI1 PAFAH1B2 PPM1A PRPF40A SMAD3 STAU1 YWHAQ	39 interactors: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TUBB TUBB4A UBE2D3 UPF1 ZMAT3
Entrez ID		6175	6780
HPRD ID		01610	03422
Ensembl ID		ENSG00000089157	ENSG00000124214
Uniprot IDs		P05388 Q3B7A4	B3KRE0 O95793 Q6PJX3
PDB IDs		3J39 3J3B	4DKK
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Cell Cycle Negative Regulation Of Cell Cycle Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Wnt Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Potassium Ion Export Cell Cycle Process Regulation Of Transcription Factor Import Into Nucleus Regulation Of Intracellular Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Morphogenesis Regulation Of Heart Rate By Hormone Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Negative Regulation Of Protein Catabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Evasion Or Tolerance Of Host Defenses By Virus Positive Regulation Of Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Regulation Of Cell Shape Negative Regulation Of SMAD Protein Complex Assembly Regulation Of Extracellular Matrix Assembly Transcription Initiation From RNA Polymerase II Promoter Regulation Of Protein Import Into Nucleus Regulation Of Establishment Of Protein Localization Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of Transport Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Osteoblast Proliferation SMAD Protein Complex Assembly Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Nucleocytoplasmic Transport N-terminal Protein Myristoylation Regulation Of Transcription, DNA-templated Regulation Of Protein Localization Negative Regulation Of Mitotic Cell Cycle Regulation Of Nucleic Acid-templated Transcription	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Intracellular Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Localization RNA Transport Cytoskeleton-dependent Intracellular Transport RNA Localization Viral Process Establishment Of Localization In Cell MRNA Processing Viral Transcription SRP-dependent Cotranslational Protein Targeting To Membrane Cellular Protein Complex Disassembly Cotranslational Protein Targeting To Membrane Protein Targeting To ER Viral Life Cycle Neuron Projection Morphogenesis Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Catabolic Process Protein Complex Disassembly RNA Splicing Cytoplasmic Transport MRNA Transport Axonogenesis Organelle Transport Along Microtubule Protein Localization To Endoplasmic Reticulum Translational Initiation Microtubule-based Transport Movement Of Cell Or Subcellular Component Microtubule-based Process Axon Development RNA Processing Translational Termination Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of Translation Cell Projection Morphogenesis Protein Targeting To Membrane RNA Export From Nucleus Cell Part Morphogenesis Translational Elongation MRNA 3'-end Processing Enzyme Linked Receptor Protein Signaling Pathway Microtubule-based Movement Developmental Cell Growth
Tagcloud ?		3months 60s brains brdu bromodeoxyuridine cacybp calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside pk postnatal proteomic pyruvate spots tk transketolase ts1cje	activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Difference) ?		3months 60s brains brdu bromodeoxyuridine cacybp calcyclin candidates comparative diphosphate disabilities ds dysregulated e14 embryos eminence fingerprinting ganglionic ndpk nucleoside pk postnatal proteomic pyruvate spots tk transketolase ts1cje	activators anaphase apc arrested asynchronous cdc20 cdh1 code consistently cyclosome e3 fluctuates hct116 impairs ligase messenger mitosis mitotic mrnas participates precedes prometaphase ribonucleic rnas transit u2os underscored
Tagcloud (Intersection) ?