RPLP0 and PAFAH1B2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		RPLP0	PAFAH1B2
Description		ribosomal protein lateral stalk subunit P0	platelet activating factor acetylhydrolase 1b catalytic subunit 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome Postsynapse Ribonucleoprotein Complex	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Cytoplasmic Translation Translation Ribosome Biogenesis	Lipid Metabolic Process Spermatogenesis Lipid Catabolic Process Positive Regulation Of Macroautophagy
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)	Adult body size ( 32376654) Blood protein levels ( 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		15 interacting genes: CSNK2A1 ERG EXOSC8 GAS7 KRI1 LINC00632 OGT PAFAH1B2 PPM1A PRPF40A PTEN SMAD3 STAU1 USP7 YWHAQ	19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1
Entrez ID		6175	5049
HPRD ID		01610	03940
Ensembl ID		ENSG00000089157	ENSG00000168092
Uniprot IDs		P05388	P68402 V9HW44
PDB IDs		4V6W 4V6X 5AJ0 6OLG 6ZM7 6ZME 6ZMI 6ZMO 8G5Z 8G60 8G6J 8K2C 8UKB 8XSX 8XSY 8XSZ 8YOO 8YOP	1VYH
Enriched GO Terms of Interacting Partners?		Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Stabilization Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Rhythmic Process Negative Regulation Of Macromolecule Metabolic Process PML Body Negative Regulation Of Protein Metabolic Process Negative Regulation Of Metabolic Process Sin3-type Complex Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Biosynthetic Process Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Gene Expression R-SMAD Binding Negative Regulation Of Catabolic Process Regulation Of Proteolysis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Identical Protein Binding Positive Regulation Of Autophagy Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Negative Regulation Of Synaptic Vesicle Clustering Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Cellular Localization Regulation Of Gluconeogenesis Cytosol Positive Regulation Of Catabolic Process Membraneless Organelle Assembly Regulation Of Gene Expression Negative Regulation Of Osteoblast Differentiation Regulation Of Cell Junction Assembly Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Focal Adhesion Assembly Negative Regulation Of Wound Healing Positive Regulation Of Nucleocytoplasmic Transport Cellular Response To Glucose Stimulus Regulation Of Intracellular Transport Response To Transforming Growth Factor Beta	1-alkyl-2-acetylglycerophosphocholine Esterase Complex Positive Regulation Of Monocyte Differentiation Response To Transforming Growth Factor Beta Cellular Response To Transforming Growth Factor Beta Stimulus Diapedesis Reelin-mediated Signaling Pathway Protein Localization To Organelle Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of ATP Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Monocyte Differentiation Regulation Of ATP Biosynthetic Process Negative Regulation Of Glycolytic Process Positive Regulation Of Myeloid Cell Differentiation Phospholipase Binding Negative Regulation Of ATP Metabolic Process Response To Glucocorticoid Intracellular Protein Localization Response To Hormone Microtubule Nucleus Regulation Of JNK Cascade Protein-containing Complex Binding Response To Corticosteroid Negative Regulation Of JNK Cascade Positive Regulation Of Cell Growth Positive Regulation Of ATP Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Localization To Mitochondrion Regulation Of Reactive Oxygen Species Biosynthetic Process RNA Binding Cell Population Proliferation Organelle Organization Negative Regulation Of Spontaneous Neurotransmitter Secretion Protein Localization To Nucleus Regulation Of Telomere Maintenance Via Telomerase Phosphotyrosine Residue Binding Regulation Of Myeloid Cell Differentiation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay Cellular Response To Raffinose Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Erythrocyte Differentiation Response To Steroid Hormone Helper T Cell Diapedesis Leukocyte Migration Positive Regulation Of Protein Localization Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin
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