RPL18 and FANCA

Number of citations of the paper that reports this interaction (PMID 14499622)
5

Data Source:
BioGRID (two hybrid)

		RPL18	FANCA
Gene Name		ribosomal protein L18	Fanconi anemia, complementation group A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleus Nucleoplasm Nucleolus Cytoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	DNA Repair Protein Complex Assembly Male Meiosis Male Gonad Development Female Gonad Development Regulation Of Cell Proliferation
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Fanconi Anemia pathway
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		4 interactors: CDKN1A FANCA FANCC IL7R	46 interactors: AKT1 ALDOA ATP5B ATR AZIN1 BRCA1 CAPN1 CCT3 CD79A CDK1 CENPE DAXX DDX39B DNAJB1 DUS4L ENO1 FANCC FANCE FANCF FANCG GNB2 HES1 HPRT1 HSP90AA1 IFIT3 IKBKB KRT1 LIPG MKNK1 MX1 NAMPT NUB1 PRPF31 PSMA5 RPL18 SGK1 SMARCA4 SMARCC1 SMARCD3 SNX5 SPTAN1 TAF10 TCERG1 TCP1 TPT1 ZNF24
Entrez ID		6141	2175
HPRD ID		16046	06186
Ensembl ID		ENSG00000063177	ENSG00000187741
Uniprot IDs		F8VWC5 Q07020	H3BSR5 O15360 Q86U55
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus Interleukin-7-mediated Signaling Pathway Homeostasis Of Number Of Cells Negative Regulation Of T Cell Mediated Cytotoxicity Intestinal Epithelial Cell Maturation Positive Regulation Of Cell Activation Cellular Response To Stress Cellular Response To UV-B Regulation Of Lymphocyte Activation Stress-induced Premature Senescence Anatomical Structure Development Negative Regulation Of T Cell Mediated Immunity Regulation Of Cell Activation Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Immune System Process Developmental Process Regulation Of Protein Import Into Nucleus, Translocation Removal Of Superoxide Radicals Intestinal Epithelial Cell Differentiation Cellular Response To Superoxide Epithelial Cell Maturation DNA Repair Response To Superoxide Response To Arsenic-containing Substance Response To Oxygen Radical Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Senescence Regulation Of T Cell Differentiation In Thymus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Developmental Process Involved In Reproduction Response To Hyperoxia Response To Corticosterone Negative Regulation Of Adaptive Immune Response Cellular Response To Stimulus Response To Mineralocorticoid B Cell Proliferation Positive Regulation Of B Cell Proliferation Superoxide Metabolic Process Organ Development Regulation Of Immune Response Columnar/cuboidal Epithelial Cell Development Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA Biosynthetic Process Positive Regulation Of Immune System Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest	Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Response To Stress Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Complex Assembly Cellular Response To Stress Peptidyl-serine Phosphorylation Metabolic Process Nucleosome Disassembly Response To Stimulus Immune System Process Positive Regulation Of Cellular Metabolic Process Cellular Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Metabolic Process Regulation Of Cellular Response To Heat Cellular Component Assembly Response To Heat Regulation Of Cellular Process Apoptotic Process Cell Cycle Checkpoint Regulation Of Protein Catabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Regulation Of Response To DNA Damage Stimulus DNA Repair Cell Cycle Process Innate Immune Response Response To Virus Cell Death Death Reproductive Process Positive Regulation Of Cellular Biosynthetic Process 'de Novo' Posttranslational Protein Folding Response To Organic Substance Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Nucleosome Organization 'de Novo' Protein Folding Positive Regulation Of Cell Cycle Positive Regulation Of Cellular Protein Catabolic Process Chromatin Assembly Or Disassembly DNA Damage Checkpoint Cellular Response To Heat Regulation Of Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Regulation Of Apoptotic Process
Tagcloud ?		19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 pla2g4c q13 radio srm zin	aml anemia aplastic autosomal brca2 collaborate complicated cumulative cure decision fancd1 fanconi fancq genotypes gynecologic head inherited neck preemptive prone recessive risks solid squamous subset transplant usually wilms
Tagcloud (Difference) ?		19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 pla2g4c q13 radio srm zin	aml anemia aplastic autosomal brca2 collaborate complicated cumulative cure decision fancd1 fanconi fancq genotypes gynecologic head inherited neck preemptive prone recessive risks solid squamous subset transplant usually wilms
Tagcloud (Intersection) ?