RPL18

Gene Name		ribosomal protein L18
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		4 interactors: CDKN1A FANCA FANCC IL7R
Entrez ID		6141
HPRD ID		16046
Ensembl ID		ENSG00000063177
Uniprot IDs		F8VWC5 Q07020
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus Interleukin-7-mediated Signaling Pathway Homeostasis Of Number Of Cells Negative Regulation Of T Cell Mediated Cytotoxicity Intestinal Epithelial Cell Maturation Positive Regulation Of Cell Activation Cellular Response To Stress Cellular Response To UV-B Regulation Of Lymphocyte Activation Stress-induced Premature Senescence Anatomical Structure Development Negative Regulation Of T Cell Mediated Immunity Regulation Of Cell Activation Lymph Node Development Positive Regulation Of T Cell Differentiation In Thymus Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Immune System Process Developmental Process Regulation Of Protein Import Into Nucleus, Translocation Removal Of Superoxide Radicals Intestinal Epithelial Cell Differentiation Cellular Response To Superoxide Epithelial Cell Maturation DNA Repair Response To Superoxide Response To Arsenic-containing Substance Response To Oxygen Radical Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Senescence Regulation Of T Cell Differentiation In Thymus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Developmental Process Involved In Reproduction Response To Hyperoxia Response To Corticosterone Negative Regulation Of Adaptive Immune Response Cellular Response To Stimulus Response To Mineralocorticoid B Cell Proliferation Positive Regulation Of B Cell Proliferation Superoxide Metabolic Process Organ Development Regulation Of Immune Response Columnar/cuboidal Epithelial Cell Development Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA Biosynthetic Process Positive Regulation Of Immune System Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Tagcloud ?		19q 19q13 1p 1p36 allelic anaplastic astrocytomas cdnas dbp deleted flj10781 ftl gliomas heterozygosity icmt loh losses mgc4399 microarrays microsatellite oligoastrocytomas oligodendroglial oligodendrogliomas p36 pla2g4c q13 radio srm zin