RPL13 and WEE2-AS1

Number of citations of the paper that reports this interaction (PubMedID 36123327)
40

Data Source:
BioGRID (unspecified method)

		RPL13	WEE2-AS1
Description		ribosomal protein L13	WEE2 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Ribosome Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse Ribonucleoprotein Complex	U1 SnRNP
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Pre-mRNA 5'-splice Site Binding
	Biological Process	Blastocyst Development Cytoplasmic Translation Translation Bone Development	MRNA 5'-splice Site Recognition
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Bipolar disorder ( 34002096) Hair morphology traits ( 30166351)
Interacting Genes		24 interacting genes: ANXA7 CEP70 CSNK2A1 CSNK2B DAXX DUX4 ERCC6 ILK IPO5 MAP2K3 MAPKAPK5 OGT PRRC2B PTEN RAD21 RELA RIPK4 SMN1 SPP1 SRPK2 TERF2 TK1 UPF2 WEE2-AS1	161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1
Entrez ID		6137	285962
HPRD ID		06428	08286
Ensembl ID		ENSG00000167526	ENSG00000228775
Uniprot IDs		A8K4C8 P26373
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QVP 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Protein Serine/threonine Kinase Activity Nucleoplasm Negative Regulation Of Cell Cycle Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Cycle Process Regulation Of RNA Metabolic Process Response To UV-B Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Protein Kinase Activity Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Protein Serine Kinase Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Cytosol Regulation Of Cell Cycle Regulation Of Primary Metabolic Process Protein Localization To Chromosome PML Body Positive Regulation Of Metabolic Process Kinase Activity Intracellular Signal Transduction Intracellular Signaling Cassette Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Modification Process Negative Regulation Of DNA Repair Regulation Of Protein Metabolic Process Nucleus Positive Regulation Of Biosynthetic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Component Assembly Negative Regulation Of Proteasomal Protein Catabolic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Senescence ATP Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process MAP Kinase Kinase Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Metabolic Process	RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization
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