RPL5 and IPO13

Number of citations of the paper that reports this interaction (PMID 11447110)
62

Data Source:
BioGRID (pull down)

		RPL5	IPO13
Gene Name		ribosomal protein L5	importin 13
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding 5S RRNA Binding Poly(A) RNA Binding	Protein Binding Ran GTPase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process	Protein Import Into Nucleus
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Height ( 20881960) Multiple sclerosis ( 19525955 17660530)
Protein-Protein Interactions		21 interactors: CSNK2A1 CSNK2B DCC EIF5A HARS IPO13 IPO5 IPO7 KPNB1 MAP3K14 MDM2 NVL PDCD4 PPM1D SPP1 SURF2 TNIP1 TNPO1 TSC22D1 UPF2 VHL	14 interactors: ALX1 CRX EIF1AX GK MAGOH NUP50 PAX3 PAX6 PBX4 PITX1 RAN RBM8A RPL5 UBE2I
Entrez ID		6125	9670
HPRD ID		04699	13742
Ensembl ID		ENSG00000122406	ENSG00000117408
Uniprot IDs		A2RUM7 B3KTM6 P46777	O94829
PDB IDs		3J3B	2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport Protein Localization To Nucleus Protein Import Into Nucleus Nuclear Import Protein Import Cytoplasmic Transport Protein Localization To Organelle Establishment Of Protein Localization To Organelle Negative Regulation Of Collateral Sprouting Ribosomal Protein Import Into Nucleus Protein Targeting NLS-bearing Protein Import Into Nucleus Intracellular Protein Transport Cellular Protein Localization Viral Process Apoptotic Process Establishment Of Protein Localization Regulation Of Cell Proliferation Programmed Cell Death Intracellular Transport Cell Death Death Protein Import Into Nucleus, Translocation Cellular Localization Response To External Stimulus Protein Localization Protein Transport Establishment Of Localization In Cell Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Cellular Response To UV-C Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cellular Response To Vitamin B1 Negative Regulation Of Axonogenesis Chemotaxis MRNA Export From Nucleus Regulation Of MAPK Cascade Histidyl-tRNA Aminoacylation Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury RNA Export From Nucleus Regulation Of Catalytic Activity Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Developmental Growth Spinal Cord Ventral Commissure Morphogenesis Netrin-activated Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cell Growth Mitotic Cell Cycle Cellular Response To Hypoxia	Gene Expression Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of RNA Metabolic Process Mesenchymal Cell Development Nuclear Export MRNA Transport Regulation Of Gene Expression Mesenchymal Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process RNA Transport Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Catabolic Process Viral Life Cycle Neural Tube Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Mesenchyme Development Viral Process Positive Regulation Of Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Neural Crest Cell Migration Stem Cell Development Embryonic Morphogenesis Nucleocytoplasmic Transport Pituitary Gland Development Nuclear Transport Metabolic Process Mitotic Cell Cycle Process Cytoplasmic Transport
Tagcloud ?		biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine imp impdh2 inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Difference) ?		biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine imp impdh2 inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Intersection) ?