ALX4 and ALX1

Number of citations of the paper that reports this interaction (PMID 9847249)
21

Data Source:
HPRD (in vitro)

		ALX4	ALX1
Gene Name		ALX homeobox 4	ALX homeobox 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Protein Heterodimerization Activity HMG Box Domain Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Skeletal System Development Hair Follicle Development Transcription, DNA-templated Muscle Organ Development Post-embryonic Development Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Embryonic Digit Morphogenesis Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Development Embryonic Skeletal System Morphogenesis Palate Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cartilage Condensation Neural Tube Closure Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Brain Development Anterior/posterior Pattern Specification Mesenchymal Cell Development Embryonic Limb Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Palate Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ALX1 CEBPE EMX1 FOXA3 GATA4 HOXA3 HOXB13 HOXB6 HOXD3 LEF1 SOX10 SOX2	5 interactors: ALX4 CREBBP EP300 IPO13 SRA1
Entrez ID		60529	8092
HPRD ID		05661	03316
Ensembl ID		ENSG00000052850	ENSG00000180318
Uniprot IDs		Q9H161	Q15699
PDB IDs		2M0C
Enriched GO Terms of Interacting Partners?		Organ Development Organ Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process System Development Embryonic Organ Development Anterior/posterior Pattern Specification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Multicellular Organismal Development Embryonic Organ Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Anatomical Structure Morphogenesis Gene Expression Embryonic Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Developmental Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Embryonic Skeletal System Morphogenesis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Embryonic Skeletal System Development Tube Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Mesenchyme Development Gland Development Morphogenesis Of An Epithelium Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Formation Involved In Morphogenesis Stem Cell Development	N-terminal Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Heat Embryonic Digit Morphogenesis Positive Regulation Of Type I Interferon Production Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Histone H2B Acetylation Cellular Response To Oxygen Levels Response To Heat Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Notch Signaling Pathway Transcription, DNA-templated Embryonic Limb Morphogenesis RNA Biosynthetic Process Limb Morphogenesis Response To Temperature Stimulus Limb Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Embryo Development Anterior/posterior Pattern Specification Peptidyl-lysine Modification Germ-line Stem Cell Maintenance Muscle Organ Development Response To Hypoxia RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process Gene Expression Positive Regulation By Host Of Viral Transcription Positive Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Histone Modification Positive Regulation Of Cellular Biosynthetic Process Pattern Specification Process
Tagcloud ?		associating candidates cooccur cooperation crebbp driver exclusive forward foxr2 gli gli1 gnp gnps granule hedgehog medulloblastoma mutagenesis mutually nih3t3 oncogenes screen shh sonic strengthening subtype tended tgif2 transposon trp53	abnormally abonormally adc adenosquamous bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra phox2a pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Difference) ?		associating candidates cooccur cooperation crebbp driver exclusive forward foxr2 gli gli1 gnp gnps granule hedgehog medulloblastoma mutagenesis mutually nih3t3 oncogenes screen shh sonic strengthening subtype tended tgif2 transposon trp53	abnormally abonormally adc adenosquamous bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra phox2a pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Intersection) ?