ALX1 and IPO13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ALX1	IPO13
Gene Name		ALX homeobox 1	importin 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Heterodimerization Activity	Protein Binding Ran GTPase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cartilage Condensation Neural Tube Closure Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Brain Development Anterior/posterior Pattern Specification Mesenchymal Cell Development Embryonic Limb Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Palate Development	Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ALX4 CREBBP EP300 IPO13 SRA1	14 interactors: ALX1 CRX EIF1AX GK MAGOH NUP50 PAX3 PAX6 PBX4 PITX1 RAN RBM8A RPL5 UBE2I
Entrez ID		8092	9670
HPRD ID		03316	13742
Ensembl ID		ENSG00000180318	ENSG00000117408
Uniprot IDs		Q15699	O94829
PDB IDs			2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Regulation Of Cellular Response To Heat Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Heat Embryonic Digit Morphogenesis Positive Regulation Of Type I Interferon Production Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Type I Interferon Production Histone H2B Acetylation Cellular Response To Oxygen Levels Response To Heat Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Notch Signaling Pathway Transcription, DNA-templated Embryonic Limb Morphogenesis RNA Biosynthetic Process Limb Morphogenesis Response To Temperature Stimulus Limb Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Embryo Development Anterior/posterior Pattern Specification Peptidyl-lysine Modification Germ-line Stem Cell Maintenance Muscle Organ Development Response To Hypoxia RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process Gene Expression Positive Regulation By Host Of Viral Transcription Positive Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Histone Modification Positive Regulation Of Cellular Biosynthetic Process Pattern Specification Process	Gene Expression Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of RNA Metabolic Process Mesenchymal Cell Development Nuclear Export MRNA Transport Regulation Of Gene Expression Mesenchymal Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process RNA Transport Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Catabolic Process Viral Life Cycle Neural Tube Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Mesenchyme Development Viral Process Positive Regulation Of Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Neural Crest Cell Migration Stem Cell Development Embryonic Morphogenesis Nucleocytoplasmic Transport Pituitary Gland Development Nuclear Transport Metabolic Process Mitotic Cell Cycle Process Cytoplasmic Transport
Tagcloud ?		abnormally abonormally adc adenosquamous bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra phox2a pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Difference) ?		abnormally abonormally adc adenosquamous bcl2 cancerous chga ema folx2 foxl2 hpp1 hypermethylation methyaltion methylated methylation msp myf6 nsclc oc2 offer pdgfra phox2a pitx2 rarb shed six6 smpd3 sox1 syn
Tagcloud (Intersection) ?