NUDT14 and TEPSIN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUDT14	TEPSIN
Description		nudix hydrolase 14	TEPSIN adaptor related protein complex 4 accessory protein
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Golgi Apparatus Cytosol Membrane Coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane
	Molecular Function	Protein Binding UDP-sugar Diphosphatase Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Identical Protein Binding Metal Ion Binding ADP-ribose Diphosphatase Activity	Protein Binding Protein-containing Complex Binding
	Biological Process	Nucleoside Phosphate Metabolic Process Protein N-linked Glycosylation Via Asparagine Ribose Phosphate Metabolic Process
Pathways		Synthesis of dolichyl-phosphate-glucose
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neutrophil count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)	IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)
Interacting Genes		11 interacting genes: ARAF LNX1 LNX2 NIF3L1 NTAQ1 RAF1 REL TEPSIN TERF1 TERF2IP ZCCHC10	126 interacting genes: AATK ACBD7 AGRN AIRIM AP1M1 APOL6 APP ASAP3 ASB3 ATOSB BCL2L14 BCL2L15 BIRC7 BPIFA1 BTBD3 C1QTNF4 CBX8 CCDC146 CCNC CDC23 CINP CLCNKA CLIC3 CNTF CPNE7 CSNK2A1 CTAG1A CTAG1B CYSRT1 DEF6 DUSP29 DUSP4 DZIP1L EIF1AD FAM90A1 FARS2 FKBP6 FLACC1 FNDC3B GNG13 GOLGA2 GPANK1 GPRASP3 GRB10 GRIPAP1 GUCD1 HAT1 HCK HPCA HSF2BP HSPB7 IL16 IQGAP1 KCTD6 KCTD9 KHNYN KLHL38 KRT31 KRT34 KRT35 KRTAP6-2 LENG1 LGALS14 LMO3 LSM3 LYG2 MAT2B MED18 MFAP1 MLX MORF4L1 MSGN1 MTUS2 NDOR1 NEK6 NGB NME7 NR2C2AP NTAQ1 NUDT14 NUDT21 OAZ3 OR6B1 PAX9 PCDHB3 PLEKHA2 PSMA6 RAB3IP RAD51D RANBP3 RNF135 SEC14L4 SLU7 SNRNP25 SORBS2 SORBS3 SZT2 TAPBPL TBC1D13 TBC1D22B TCEA2 TCL1A TFAP2D THRSP TRAPPC2 TRAPPC2B TRAPPC6A TRIM23 TRIM45 TRIM50 TRIM54 TRIM68 TSEN15 TSEN2 TSHZ3 TSSK3 UBASH3B UTP23 VPS26C WDR25 YPEL3 ZIC1 ZMYND12 ZNF343 ZNF629 ZRSR2
Entrez ID		256281	146705
HPRD ID		14847	08103
Ensembl ID		ENSG00000183828	ENSG00000167302
Uniprot IDs		B3KXY7 O95848	A0A1B0GV70 Q96N21
PDB IDs		3Q91 8OTV	5WF9 5WFB
Enriched GO Terms of Interacting Partners?		Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping MAP Kinase Kinase Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Protein-N-terminal Glutamine Amidohydrolase Activity Coated Vesicle Membrane Death-inducing Signaling Complex Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Protein-N-terminal Asparagine Amidohydrolase Activity PDZ Domain Binding DNA Biosynthetic Process Regulation Of Protein Phosphorylation Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Phosphorylation Regulation Of Telomere Maintenance NF-kappaB Complex Telomere Organization Adenylate Cyclase Activator Activity Identical Protein Binding Negative Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Zinc Ion Binding Regulation Of Phosphorus Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Telomere Localization Meiotic Telomere Clustering Telomeric D-loop Disassembly	Protein Binding Nucleus Identical Protein Binding TRAPPIII Protein Complex
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