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NUDT14
Description
nudix hydrolase 14
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Molecular Function
Protein Binding
UDP-sugar Diphosphatase Activity
Hydrolase Activity
Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides
Identical Protein Binding
Metal Ion Binding
ADP-ribose Diphosphatase Activity
Biological Process
Nucleoside Phosphate Metabolic Process
Protein N-linked Glycosylation Via Asparagine
Ribose Phosphate Metabolic Process
Pathways
Synthesis of dolichyl-phosphate-glucose
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Immature fraction of reticulocytes (
32888494
)
Neutrophil count (
32888494
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
11 interacting genes:
ARAF
LNX1
LNX2
NIF3L1
NTAQ1
RAF1
REL
TEPSIN
TERF1
TERF2IP
ZCCHC10
Entrez ID
256281
HPRD ID
14847
Ensembl ID
ENSG00000183828
Uniprot IDs
B3KXY7
O95848
PDB IDs
3Q91
8OTV
Enriched GO Terms of Interacting Partners
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Nuclear Telomere Cap Complex
Shelterin Complex
G-rich Strand Telomeric DNA Binding
Telomere Capping
MAP Kinase Kinase Kinase Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Telomere Maintenance Via Telomerase
RNA-templated DNA Biosynthetic Process
Regulation Of Peptidyl-serine Phosphorylation
Telomere Maintenance Via Telomere Lengthening
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Positive Regulation Of Shelterin Complex Assembly
Protein-N-terminal Glutamine Amidohydrolase Activity
Coated Vesicle Membrane
Death-inducing Signaling Complex Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Chromosome Organization
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of DNA Recombination At Telomere
Protein-N-terminal Asparagine Amidohydrolase Activity
PDZ Domain Binding
DNA Biosynthetic Process
Regulation Of Protein Phosphorylation
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Regulation Of Phosphorylation
Regulation Of Telomere Maintenance
NF-kappaB Complex
Telomere Organization
Adenylate Cyclase Activator Activity
Identical Protein Binding
Negative Regulation Of DNA Metabolic Process
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Chromosome
Telomerase Activity
Ankyrin Repeat Binding
Protection From Non-homologous End Joining At Telomere
Zinc Ion Binding
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
ERBB2-ERBB3 Signaling Pathway
ERBB3 Signaling Pathway
Telomere Localization
Meiotic Telomere Clustering
Telomeric D-loop Disassembly
Tagcloud
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