DCTD and NIF3L1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DCTD	NIF3L1
Gene Name		dCMP deaminase	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Cytoplasm Mitochondrion
	Molecular Function	DCMP Deaminase Activity Zinc Ion Binding	GTP Cyclohydrolase I Activity Protein Binding GTP Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleotide Biosynthetic Process Small Molecule Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Positive Regulation Of Transcription, DNA-templated
Pathways		Pyrimidine biosynthesis Pyrimidine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		9 interactors: CEP76 FGF12 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 SDCBP TXN2	64 interactors: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FAM49B FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1
Entrez ID		1635	60491
HPRD ID		09623	10424
Ensembl ID		ENSG00000129187	ENSG00000196290
Uniprot IDs		P32321	Q9GZT8
PDB IDs		2W4L
Enriched GO Terms of Interacting Partners?		GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Mitochondrial Translation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Negative Regulation Of Ribosome Biogenesis Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Regulation Of Mitochondrial Translation Regulation Of Organelle Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Centriole Replication Substrate-dependent Cell Migration, Cell Extension Purine Ribonucleoside Catabolic Process	Protein Oligomerization Nucleobase-containing Compound Metabolic Process Protein Tetramerization Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Nitrogen Compound Metabolic Process Nucleoside Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Protein Complex Assembly Protein Homotetramerization Purine Nucleoside Metabolic Process Protein Homooligomerization Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Metabolic Process Polyamine Catabolic Process Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination Nucleotide Metabolic Process Amine Metabolic Process Ribonucleotide Metabolic Process Biosynthetic Process Cellular Metabolic Process Purine Nucleotide Metabolic Process S-adenosylmethionine Metabolic Process Methionine Metabolic Process Regulation Of Protein Homodimerization Activity Cellular Component Assembly Sulfation Sulfur Compound Metabolic Process Positive Regulation Of T Cell Activation Gene Expression Amine Biosynthetic Process Oocyte Maturation Positive Regulation Of Homotypic Cell-cell Adhesion Transcription, DNA-templated Regulation Of Glycolytic Process Meiosis I Organophosphate Metabolic Process Male Meiosis I Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell-cell Adhesion RNA Biosynthetic Process Response To Injury Involved In Regulation Of Muscle Adaptation Deoxyhypusine Biosynthetic Process From Spermidine Glucose Mediated Signaling Pathway Polyamine Homeostasis Response To Brefeldin A
Tagcloud ?		catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates
Tagcloud (Difference) ?		catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates
Tagcloud (Intersection) ?