DCTD and FGF12

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DCTD	FGF12
Gene Name		dCMP deaminase	fibroblast growth factor 12
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Extracellular Space Nucleus
	Molecular Function	DCMP Deaminase Activity Zinc Ion Binding	Fibroblast Growth Factor Receptor Binding Growth Factor Activity Heparin Binding Sodium Channel Regulator Activity Ion Channel Binding
	Biological Process	Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleotide Biosynthetic Process Small Molecule Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process	Regulation Of Membrane Depolarization Signal Transduction JNK Cascade Cell-cell Signaling Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity
Pathways		Pyrimidine biosynthesis Pyrimidine metabolism Metabolism of nucleotides
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)	Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Sleep quality ( 23728906)
Protein-Protein Interactions		9 interactors: CEP76 FGF12 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 SDCBP TXN2	13 interactors: APP COIL DACH1 DCTD IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L SRPK1 SRPK2 ZNF460
Entrez ID		1635	2257
HPRD ID		09623	03303
Ensembl ID		ENSG00000129187	ENSG00000114279
Uniprot IDs		P32321	P61328
PDB IDs		2W4L	1Q1U
Enriched GO Terms of Interacting Partners?		GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Negative Regulation Of Mitochondrial Translation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Negative Regulation Of Ribosome Biogenesis Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Regulation Of Mitochondrial Translation Regulation Of Organelle Organization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Centriole Replication Substrate-dependent Cell Migration, Cell Extension Purine Ribonucleoside Catabolic Process	Negative Regulation Of Sodium Ion Transport RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Nucleobase-containing Compound Metabolic Process Regulation Of Transmembrane Transporter Activity Positive Regulation Of Viral Genome Replication Gene Expression Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Suckling Behavior Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mating Behavior Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process Negative Regulation Of Viral Genome Replication Regulation Of Membrane Potential Regulation Of Metabolic Process Mating Neuromuscular Junction Development Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sodium Ion Transport Regulation Of MRNA Splicing, Via Spliceosome Response To Stress Positive Regulation Of Neutrophil Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Cellular Metabolic Process Negative Regulation Of Viral Process Response To Osmotic Stress Regulation Of MRNA Processing Regulation Of Synapse Structure Or Activity Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport MRNA Processing Feeding Behavior
Tagcloud ?		catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates	bisulfite breed broilers cgis chicken chickens contrasts cr1 differentially exons fgf14 fgf18 fgfr2 fgfr3 intergenic introns medip methylated poultry prominently recessive rock seq tails utrs validate wrr xh xinhua
Tagcloud (Difference) ?		catabolism consequent cytidine deaminase deoxycytidine deoxyguanosine deoxyribonucleoside deoxyribonucleosides deoxyribonucleotide depletion disrupt dn dns dntp dntps encephalomyopathy immucillin mngie mtdna neurogastrointestinal nucleoside phosphorylase purine spite supplements tetrahydrouridine thu thymidine triphosphates	bisulfite breed broilers cgis chicken chickens contrasts cr1 differentially exons fgf14 fgf18 fgfr2 fgfr3 intergenic introns medip methylated poultry prominently recessive rock seq tails utrs validate wrr xh xinhua
Tagcloud (Intersection) ?