RGS1 and TSC22D1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RGS1	TSC22D1
Description		regulator of G protein signaling 1	TSC22 domain family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding	Transcription Coactivator Activity Protein Binding Identical Protein Binding
	Biological Process	Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Response To Bacterium Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Leukotriene Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Hematopoietic Stem Cell Proliferation
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Celiac disease ( 18311140 20190752 22057235 30572963) Multiple sclerosis ( 21833088 24076602 27386562) Systemic lupus erythematosus ( 28714469 33536424) Systemic vasculitis ( 29374629) Type 1 diabetes ( 34127860)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)
Interacting Genes		9 interacting genes: APP FBXO7 FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A	51 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC90B CFTR CHD3 CORO2B CRMP1 DDAH2 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 HMGXB4 KMT2B KMT2C LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1
Entrez ID		5996	8848
HPRD ID		15968	07414
Ensembl ID		ENSG00000090104	ENSG00000102804
Uniprot IDs		Q08116	A8K3Y6 Q15714
PDB IDs		2BV1 2GTP
Enriched GO Terms of Interacting Partners?		Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Cellular Response To Catecholamine Stimulus Response To Catecholamine Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Amyloid-beta Complex Dendritic Shaft Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Skeletal Muscle Contraction By Modulation Of Calcium Ion Sensitivity Of Myofibril Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Ethanolamine Metabolic Process Glycerophosphoinositol Glycerophosphodiesterase Activity G Protein-coupled Receptor Signaling Pathway Autophagy Of Mitochondrion Regulation Of Cell Communication Regulation Of Signaling Acetylcholine Receptor Activator Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Cell Body Lipoprotein Particle Positive Regulation Of Signal Transduction Positive Regulation Of Protein Import Defense Response To Gram-negative Bacterium Mu-type Opioid Receptor Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Transport Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization G Protein-coupled Serotonin Receptor Binding Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Lewy Body Core Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Corticotropin-releasing Hormone Receptor 1 Binding	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Nucleus Nucleoplasm Negative Regulation Of Cell Communication Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Signaling Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity
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