RGS1 and TSC22D1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RGS1	TSC22D1
Gene Name		regulator of G-protein signaling 1	TSC22 domain family, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nucleus Cytoplasm
	Molecular Function	GTPase Activator Activity Calmodulin Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Immune Response Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS		Celiac disease ( 20190752 18311140) Multiple sclerosis ( 21833088)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)
Protein-Protein Interactions		8 interactors: APP FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A	49 interactors: A2M APLP1 ASAH1 C14orf1 C9orf9 CACNA1A CARHSP1 CCDC90B CHD3 CORO2B CRMP1 DDAH2 DNMT3B EED FAF1 FAM20C FBN3 GNB2 GNB5 HMGXB4 KMT2B KMT2C LRIF1 MAP3K12 MCM3AP NCOA5 OTUB1 PDHB PRKCI PTN QARS RGS1 RPL5 SETDB1 SP110 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WDYHV1 WIZ WNK1 ZC3HC1
Entrez ID		5996	8848
HPRD ID		15968	07414
Ensembl ID		ENSG00000090104
Uniprot IDs		Q08116	A8K3Y6 Q15714
PDB IDs		2BV1 2GTP
Enriched GO Terms of Interacting Partners?			Regulation Of Metabolic Process Chromatin Organization Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Protein Metabolic Process Chromosome Organization Regulation Of Chromosome Organization Regulation Of Histone Modification Regulation Of Protein Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Methylation Histone Modification Gene Expression Cellular Nitrogen Compound Metabolic Process Peptidyl-threonine Phosphorylation RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Signal Transduction Heterocycle Metabolic Process Regulation Of Histone Methylation Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Signal Transduction Transcription, DNA-templated Cellular Response To Stimulus Negative Regulation Of Signaling Regulation Of Phosphorus Metabolic Process Response To Stimulus Protein Methylation Positive Regulation Of Histone Modification Regulation Of Transcription, DNA-templated Organelle Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Signaling Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Cell Communication Histone Lysine Methylation Negative Regulation Of Chromosome Organization Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular	beadchip capn13 cards cic collect conjunctival cxcl6 cytology drb5 dry entire eye ht illumina impression investigates lysozyme mini optimally optimization psca qiagen qrt qualifying rneasy severities steps taqman transcriptome
Tagcloud (Difference) ?		aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular	beadchip capn13 cards cic collect conjunctival cxcl6 cytology drb5 dry entire eye ht illumina impression investigates lysozyme mini optimally optimization psca qiagen qrt qualifying rneasy severities steps taqman transcriptome
Tagcloud (Intersection) ?