RGS1 and GDE1

Number of citations of the paper that reports this interaction (PMID 10760272)
14

Data Source:
HPRD (two hybrid)

		RGS1	GDE1
Gene Name		regulator of G-protein signaling 1	glycerophosphodiester phosphodiesterase 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Cytoplasm Integral Component Of Membrane
	Molecular Function	GTPase Activator Activity Calmodulin Binding	Glycerophosphodiester Phosphodiesterase Activity Metal Ion Binding Glycerophosphoinositol Glycerophosphodiesterase Activity
	Biological Process	Immune Response Signal Transduction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	Glycerol Metabolic Process Lipid Metabolic Process
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events
Drugs
Diseases
GWAS		Celiac disease ( 20190752 18311140) Multiple sclerosis ( 21833088)
Protein-Protein Interactions		8 interactors: APP FUNDC2 GDE1 GIPC1 GNAO1 MAP3K12 TSC22D1 UTP14A	5 interactors: CLGN RGS1 RGS16 RGS19 RGS2
Entrez ID		5996	51573
HPRD ID		15968	12070
Ensembl ID		ENSG00000090104	ENSG00000006007
Uniprot IDs		Q08116	Q9NZC3
PDB IDs		2BV1 2GTP
Enriched GO Terms of Interacting Partners?			Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Positive Regulation Of Metabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Binding Of Sperm To Zona Pellucida Brown Fat Cell Differentiation Sexual Reproduction Sperm-egg Recognition Regulation Of Smooth Muscle Contraction Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell-cell Recognition Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Reproduction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction
Tagcloud ?		aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular	acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual
Tagcloud (Difference) ?		aborted adjust adversely agb1 agg annotations atgpa1 atrgs1 col compartmentalization concerted conferred connecting contrasting crop drought elevate fluctuation galpha gbeta gbetagamma heterotrimeric irrigation prompted quantitated salinity salt shoot singular	acuity architecture cerevisiae cohorts cortex disequilibrium glycerophosphocholine gpcpd1 heritable homolog imputed linkage metaanalysis occipital perception phosphodiesterase proportional remainder replicated rs238295 rs6116869 saccharomyces snp snps threefold underlie utr varies visual
Tagcloud (Intersection) ?