RBBP6 and APOH

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		RBBP6	APOH
Gene Name		retinoblastoma binding protein 6	apolipoprotein H (beta-2-glycoprotein I)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Microtubule Organizing Center	Extracellular Space Cell Surface Extracellular Matrix Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Chylomicron Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding	Glycoprotein Binding Protein Binding Phospholipid Binding Heparin Binding Lipid Binding Identical Protein Binding Lipoprotein Lipase Activator Activity
	Biological Process	In Utero Embryonic Development Multicellular Organism Growth Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Somite Development	Negative Regulation Of Endothelial Cell Proliferation Triglyceride Metabolic Process Blood Coagulation, Intrinsic Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Plasminogen Activation Negative Regulation Of Myeloid Cell Apoptotic Process Triglyceride Transport Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Lipoprotein Lipase Activity Regulation Of Fibrinolysis Negative Regulation Of Fibrinolysis
Pathways
Drugs
Diseases
GWAS		Brain structure ( 20171287) Obesity-related traits ( 23251661)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374)
Protein-Protein Interactions		32 interactors: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CD81 ETS1 EVA1C FBXO7 GLUL GRB2 HP KHDRBS3 LINC00305 LRCH4 MAD2L2 NDUFB9 NEK6 PIAS1 PLG RBP4 RPS14 SMN1 SPP1 TPT1 UBE2I UPF3B VAV2 WBSCR16 YBX1 ZBTB38 ZFYVE9	14 interactors: AKT1 ANXA2 CDC42 CLEC4G F10 F12 GEM GRB2 LPA LRP2 LRP8 PLG RBBP6 TP53
Entrez ID		5930	350
HPRD ID		02964	00728
Ensembl ID		ENSG00000122257	ENSG00000091583
Uniprot IDs		Q7Z6E9	P02749
PDB IDs		2C7H 2YSA 2YUR 3ZTG	1C1Z 1G4F 1G4G 1QUB 2KRI 3OP8 4JHS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Cellular Component Assembly Negative Regulation Of Fibrinolysis Wound Healing Regulation Of Fibrinolysis Blood Coagulation Hemostasis Response To Wounding Response To External Stimulus Regulation Of Blood Coagulation Response To Stress Protein Sumoylation Regulation Of Wound Healing Mitotic Nuclear Division Regulation Of Body Fluid Levels Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Signaling Positive Regulation Of Blood Coagulation Regulation Of Immune System Process Immune System Process Reproductive Process Endocytosis Positive Regulation Of Coagulation Negative Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of SUMO Transferase Activity Protein Complex Assembly Positive Regulation Of Wound Healing Positive Regulation Of Metabolic Process Placenta Development Platelet Activation Cell Division Regulation Of Cell Proliferation Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Blood Coagulation Posttranscriptional Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Labyrinthine Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Differentiation Regulation Of Lipid Kinase Activity Negative Regulation Of Coagulation Glutamine Biosynthetic Process	Regulation Of Body Fluid Levels Blood Coagulation Hemostasis Wound Healing Response To Wounding Fibrinolysis Positive Regulation Of Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Response To Radiation Negative Regulation Of Wound Healing Labyrinthine Layer Development Organ Development Embryonic Organ Development Vesicle-mediated Transport Immune System Process In Utero Embryonic Development T Cell Costimulation Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Blood Coagulation Endocytosis Positive Regulation Of Protein Metabolic Process Regulation Of Fibrinolysis Positive Regulation Of Protein Phosphorylation Response To Light Stimulus Multicellular Organism Growth Embryonic Placenta Development Immune Response Receptor-mediated Endocytosis Regulation Of Phosphorylation Blood Coagulation, Intrinsic Pathway Regulation Of Wound Healing Regulation Of Cell-cell Adhesion Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Organelle Organization System Development Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Protein Modification Process Labyrinthine Layer Blood Vessel Development Regulation Of Organelle Organization Proteolysis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Growth
Tagcloud ?		associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs	avoiding cdc42 crosstalk dialog diffusible genomics germ highlighting inaccessible integrative interactomics interlaced juxtacrine membranome microsurgery mining ngfr omics pla secretome secretomes seminiferous sertoli spermatogenesis surrounded testicular tf transcriptomics tubules
Tagcloud (Difference) ?		associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs	avoiding cdc42 crosstalk dialog diffusible genomics germ highlighting inaccessible integrative interactomics interlaced juxtacrine membranome microsurgery mining ngfr omics pla secretome secretomes seminiferous sertoli spermatogenesis surrounded testicular tf transcriptomics tubules
Tagcloud (Intersection) ?