RBBP6 and RPS14

Number of citations of the paper that reports this interaction (PMID 18851979)
7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBBP6	RPS14
Gene Name		retinoblastoma binding protein 6	ribosomal protein S14
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Microtubule Organizing Center	Nucleolus Cytoplasm Mitochondrion Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding Translation Regulator Activity MRNA 5'-UTR Binding
	Biological Process	In Utero Embryonic Development Multicellular Organism Growth Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Somite Development	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Erythrocyte Differentiation Maturation Of SSU-rRNA Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Brain structure ( 20171287) Obesity-related traits ( 23251661)	Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		32 interactors: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CD81 ETS1 EVA1C FBXO7 GLUL GRB2 HP KHDRBS3 LINC00305 LRCH4 MAD2L2 NDUFB9 NEK6 PIAS1 PLG RBP4 RPS14 SMN1 SPP1 TPT1 UBE2I UPF3B VAV2 WBSCR16 YBX1 ZBTB38 ZFYVE9	8 interactors: APP CALM1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33
Entrez ID		5930	6208
HPRD ID		02964	00562
Ensembl ID		ENSG00000122257	ENSG00000164587
Uniprot IDs		Q7Z6E9	P62263
PDB IDs		2C7H 2YSA 2YUR 3ZTG	3J3A
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Cellular Component Assembly Negative Regulation Of Fibrinolysis Wound Healing Regulation Of Fibrinolysis Blood Coagulation Hemostasis Response To Wounding Response To External Stimulus Regulation Of Blood Coagulation Response To Stress Protein Sumoylation Regulation Of Wound Healing Mitotic Nuclear Division Regulation Of Body Fluid Levels Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Signaling Positive Regulation Of Blood Coagulation Regulation Of Immune System Process Immune System Process Reproductive Process Endocytosis Positive Regulation Of Coagulation Negative Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of SUMO Transferase Activity Protein Complex Assembly Positive Regulation Of Wound Healing Positive Regulation Of Metabolic Process Placenta Development Platelet Activation Cell Division Regulation Of Cell Proliferation Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Blood Coagulation Posttranscriptional Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Labyrinthine Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Differentiation Regulation Of Lipid Kinase Activity Negative Regulation Of Coagulation Glutamine Biosynthetic Process	Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Platelet Degranulation Random Inactivation Of X Chromosome Protein Stabilization Growth Secretion By Cell Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Synaptic Growth At Neuromuscular Junction Regulation Of Protein Stability Secretion Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Protein Import Into Peroxisome Matrix, Translocation Collateral Sprouting In Absence Of Injury Zygotic Specification Of Dorsal/ventral Axis Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Transcription Initiation From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity Cellular Protein Modification Process Platelet Activation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Primary MiRNA Processing Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Nodal Signaling Pathway Axon Choice Point Recognition Common-partner SMAD Protein Phosphorylation DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Neuron Remodeling Regulation Of Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Developmental Growth Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription From RNA Polymerase II Promoter Detection Of Calcium Ion SMAD Protein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Dosage Compensation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs	aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus
Tagcloud (Difference) ?		associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs	aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus
Tagcloud (Intersection) ?