FKBP2

Name	FKBP prolyl isomerase 2
Structure
Novel Interactors	1 novel interactors: MAP3K11
Interactors	14 interactors: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN2 UBQLN4 VAMP2
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Isomerase Activity
GWAS	Bipolar disorder ( 34002096 ) Crohn's disease ( 28067908 ) Fruit consumption ( 32066663 )
Entrez ID	2286
HPRD ID	01742
Ensembl ID	ENSG00000173486
Uniprot IDs	A0A494C1N0 P26885 Q53XJ5
PDB IDs	2PBC 4NNR
GO Terms Enriched among Interactors ?	Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of ERAD Pathway Regulation Of Cellular Response To Stress Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Localization To Cell Cortex Regulation Of Proteolysis Regulation Of Macroautophagy Positive Regulation Of Protein Catabolic Process Regulation Of Protein Localization To Cell Cortex Autophagosome Organelle Organization Autophagosome Assembly Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Catabolic Process Myosin V Binding Autophagosome Organization Autophagy Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Cytosol Regulation Of Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Spectrin Binding Regulation Of Autophagy Perinuclear Region Of Cytoplasm Cortical Actin Cytoskeleton Organization Negative Regulation Of Transport Vacuole Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Establishment Of Protein Localization Trans-Golgi Network Cytoplasmic Vesicle Exocytosis Positive Regulation Of Proteolysis Cortical Cytoskeleton Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Peptidyl-cysteine Methylation Negative Regulation Of Store-operated Calcium Channel Activity Response To Endoplasmic Reticulum Stress Regulation Of Vesicle-mediated Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process