FKBP2 and RAB3C

Number of citations of the paper that reports this interaction (PMID 22956769)
16

Data Source:
BioGRID (pull down)

		FKBP2	RAB3C
Gene Name		FK506 binding protein 2, 13kDa	RAB3C, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome	Endosome Cytosol Plasma Membrane Synaptic Vesicle Secretory Granule Membrane Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Antigen Processing And Presentation Rab Protein Signal Transduction Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		13 interactors: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2	3 interactors: FKBP2 RIMS2 RPH3AL
Entrez ID		2286	115827
HPRD ID		01742	06704
Ensembl ID		ENSG00000173486	ENSG00000152932
Uniprot IDs		P26885 Q53XJ5	Q96E17
PDB IDs		2PBC
Enriched GO Terms of Interacting Partners?		Ras Protein Signal Transduction Cortical Actin Cytoskeleton Organization Regulation Of Protein Metabolic Process Establishment Of Protein Localization Endomembrane System Organization Cortical Cytoskeleton Organization Small GTPase Mediated Signal Transduction Protein Localization Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Cellular Protein Localization Immune System Process Negative Regulation Of Apolipoprotein Binding Positive Regulation Of Protein Glycosylation In Golgi Vesicle-mediated Transport Exocytosis Protein Localization To Membrane Cellular Localization Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Regulation Of Intracellular Transport Neurotransmitter Secretion Synaptic Vesicle Transport Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Eosinophil Degranulation Regulation Of Cellular Localization Intracellular Signal Transduction Regulation Of Golgi Inheritance Positive Regulation Of Protein Glycosylation Secretion By Cell Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Neurotransmitter Levels Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Regulation Of Protein Binding Protein Localization To Plasma Membrane Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Protein Export From Nucleus Neurotransmitter Transport Actin Cytoskeleton Organization Organelle Organization Regulation Of Golgi Organization Protein K6-linked Ubiquitination Negative Regulation Of Granulocyte Differentiation	Regulation Of Exocytosis Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Exocytosis Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Of Neurotransmitter Secretion By Cell Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Secretion Secretion CAMP-mediated Signaling Cyclic-nucleotide-mediated Signaling Positive Regulation Of Excitatory Postsynaptic Membrane Potential Intracellular Protein Transport Membrane Hyperpolarization Positive Regulation Of Membrane Potential Insulin Secretion Regulation Of Cellular Localization Calcium Ion-dependent Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Chaperone-mediated Protein Folding Peptide Hormone Secretion Peptide Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Protein Localization Regulation Of Postsynaptic Membrane Potential Protein Transport Protein Peptidyl-prolyl Isomerization Vesicle-mediated Transport Hormone Secretion Establishment Of Protein Localization Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Hormone Transport Intracellular Transport Peptide Transport Neurotransmitter Secretion Membrane Depolarization Protein Secretion Amide Transport Regulation Of Neurotransmitter Levels Second-messenger-mediated Signaling Protein Localization Establishment Of Localization In Cell Neurotransmitter Transport Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion Glucose Homeostasis
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