REPS2 and RALBP1

Number of citations of the paper that reports this interaction (PMID 9422736)
27

Data Source:
HPRD (in vitro, two hybrid)

		REPS2	RALBP1
Gene Name		RALBP1 associated Eps domain containing 2	ralA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytosol Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding
	Biological Process	Protein Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1	27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707
Entrez ID		9185	10928
HPRD ID		02262	09013
Ensembl ID		ENSG00000169891	ENSG00000017797
Uniprot IDs		B4DQQ8 Q8NFH8	Q15311
PDB IDs		1IQ3	2KWH 2KWI
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Regulation Of Schwann Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Hormone Stimulus Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Regulation Of Intracellular Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Reactive Oxygen Species Cellular Response To Peptide Positive Regulation Of Catalytic Activity Response To Peptide Hormone Response To Hormone Cellular Response To Organonitrogen Compound Response To Peptide Response To Reactive Oxygen Species Protein Complex Assembly Cellular Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Ras Protein Signal Transduction Fc-epsilon Receptor Signaling Pathway Cellular Response To Organic Substance Small GTPase Mediated Signal Transduction Negative Regulation Of Signaling Endocytosis Signal Transduction Fc Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Toll-like Receptor 10 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Cellular Response To Hydrogen Peroxide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway	Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation
Tagcloud ?		amphiphysin arrays bioinformatics bridging cytoskeleton differently ectopic endocytosis leaving linking machinery mammals motifs mutagenic partner phage pob1 predictions proline ralbp1 recruiting rich scaffold sh3 spaced traffic transferrin unaffected vesicular	abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Difference) ?		amphiphysin arrays bioinformatics bridging cytoskeleton differently ectopic endocytosis leaving linking machinery mammals motifs mutagenic partner phage pob1 predictions proline recruiting rich scaffold sh3 spaced traffic transferrin unaffected vesicular	abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Intersection) ?		ralbp1