RGL4 and RALA

Number of citations of the paper that reports this interaction (PMID 12874025)
7

Data Source:
HPRD (in vitro)

		RGL4	RALA
Gene Name		ral guanine nucleotide dissociation stimulator-like 4	v-ral simian leukemia viral oncogene homolog A (ras related)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Midbody Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity	Cytokinesis Exocytosis Chemotaxis Signal Transduction Ras Protein Signal Transduction Viral Process Regulation Of Exocytosis Actin Cytoskeleton Reorganization Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways			Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events Translocation of GLUT4 to the plasma membrane NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: HRAS RALA RALB RAP1A	32 interactors: ARF1 CALM1 CNKSR2 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA HRAS LRPAP1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RAP1A RAP2A RAP2B RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		266747	5898
HPRD ID		11528	01549
Ensembl ID		ENSG00000159496	ENSG00000006451
Uniprot IDs		Q8IZJ4	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Exocytosis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Projection Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Kinase Activity Regulation Of Cell Projection Organization Positive Regulation Of Kinase Activity Intracellular Signal Transduction Cellular Response To Organic Substance Activation Of MAPKK Activity Regulation Of Cellular Component Organization Positive Regulation Of Transferase Activity Regulation Of Secretion Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Cytokinesis Response To Organic Substance Regulation Of Kinase Activity Regulation Of Cell Projection Assembly Regulation Of Exocyst Assembly Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Cell Surface Receptor Signaling Pathway Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Regulation Of Cellular Localization Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Membrane Raft Localization Regulation Of Phosphorylation Cell Cycle Positive Regulation Of Rac Protein Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of MiRNA Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Synaptic Transmission	Exocytosis Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Membrane Organization Secretion By Cell Intracellular Signal Transduction Secretion Ras Protein Signal Transduction Establishment Of Protein Localization Protein Localization Vesicle Docking Protein Transport Membrane Docking Rap Protein Signal Transduction Establishment Of Localization In Cell Cellular Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Protein Autophosphorylation Regulation Of Signaling Post-Golgi Vesicle-mediated Transport Transport Regulation Of Protein Autophosphorylation Organelle Organization Regulation Of Signal Transduction Golgi Vesicle Transport Exocyst Localization Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Platelet Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Signaling Cellular Protein Complex Localization Blood Coagulation Cell Communication Positive Regulation Of Ras GTPase Activity Hemostasis Positive Regulation Of Hydrolase Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of GTPase Activity Protein Complex Localization Cellular Response To Stimulus Regulation Of Cell Projection Organization Regulation Of GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Body Fluid Levels Wound Healing Golgi To Plasma Membrane Transport
Tagcloud ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto ralb recognition recognize regressions remarkable retrovirally termed
Tagcloud (Difference) ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto ralb recognition recognize regressions remarkable retrovirally termed
Tagcloud (Intersection) ?