RGL4 and RALB

Number of citations of the paper that reports this interaction (PMID 12874025)
7

Data Source:
HPRD (in vitro)

		RGL4	RALB
Gene Name		ral guanine nucleotide dissociation stimulator-like 4	v-ral simian leukemia viral oncogene homolog B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle	Exocyst Autophagic Vacuole Plasma Membrane Midbody Extracellular Vesicular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	GTPase Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity	Cytokinesis Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagic Vacuole Assembly
Pathways			Signalling to ERKs Signalling by NGF Signalling to RAS p38MAPK events NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: HRAS RALA RALB RAP1A	6 interactors: CALM1 PLCD1 RALBP1 REPS1 REPS2 RGL4
Entrez ID		266747	5899
HPRD ID		11528	01550
Ensembl ID		ENSG00000159496	ENSG00000144118
Uniprot IDs		Q8IZJ4	B4E040 P11234 Q6ZS74
PDB IDs			2KE5 2KWI
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Small GTPase Mediated Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Exocytosis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Projection Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Protein Kinase Activity Regulation Of Cell Projection Organization Positive Regulation Of Kinase Activity Intracellular Signal Transduction Cellular Response To Organic Substance Activation Of MAPKK Activity Regulation Of Cellular Component Organization Positive Regulation Of Transferase Activity Regulation Of Secretion Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Cytokinesis Response To Organic Substance Regulation Of Kinase Activity Regulation Of Cell Projection Assembly Regulation Of Exocyst Assembly Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Cell Surface Receptor Signaling Pathway Regulation Of Exocyst Localization Positive Regulation Of Autophagic Vacuole Assembly Positive Regulation Of Vacuole Organization Regulation Of Cellular Localization Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Membrane Raft Localization Regulation Of Phosphorylation Cell Cycle Positive Regulation Of Rac Protein Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of MiRNA Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Synaptic Transmission	Inositol Phosphate Metabolic Process Intracellular Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Hydrolase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Signal Transduction Detection Of Calcium Ion Alcohol Metabolic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Signaling Cell Communication Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cdc42 GTPase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Cdc42 GTPase Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Labyrinthine Layer Blood Vessel Development Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Autophosphorylation Cellular Response To Stimulus Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine
Tagcloud ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Difference) ?			adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncr1 ncrs nk nkp46 partly proto rala recognition recognize regressions remarkable retrovirally termed
Tagcloud (Intersection) ?