RAD51C and RAD51D

Number of citations of the paper that reports this interaction (PMID 10749867)
49

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		RAD51C	RAD51D
Gene Name		RAD51 paralog C	RAD51 paralog D
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Rad51B-Rad51C-Rad51D-XRCC2 Complex Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm Holliday Junction Resolvase Complex	Chromosome, Telomeric Region Nucleus Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Sister Chromatid Cohesion Female Meiosis Sister Chromatid Cohesion Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Strand Invasion
Pathways		Meiotic recombination Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Primary tooth development (time to first tooth eruption) ( 23704328) Testicular germ cell tumor ( 23666239 23666240)
Protein-Protein Interactions		6 interactors: APP RAD51 RAD51B RAD51D SWSAP1 XRCC3	17 interactors: AMOTL2 BLM C1orf94 CEP57L1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C SWSAP1 XRCC2 XRCC3 ZSWIM7
Entrez ID		5889	5892
HPRD ID		04143	04261
Ensembl ID		ENSG00000108384	ENSG00000185379
Uniprot IDs		O43502	O75771
PDB IDs			2KZ3
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Reciprocal Meiotic Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Meiosis I Positive Regulation Of Mitotic Cell Cycle Cellular Response To Stress Meiotic Nuclear Division Response To Stress Meiotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Mitotic Recombination Positive Regulation Of Cell Cycle Reproduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle G2/M Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process Cellular Response To Stimulus Synaptic Growth At Neuromuscular Junction Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion Collateral Sprouting In Absence Of Injury Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Response To Camptothecin Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition DNA Recombinase Assembly Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Cycle Process Positive Regulation Of Spindle Checkpoint Axon Choice Point Recognition	Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Organelle Organization Positive Regulation Of Mitotic Cell Cycle DNA Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Nuclear Division Response To X-ray Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Positive Regulation Of Cell Cycle Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neutrophil Differentiation Histone H3-R26 Methylation Inner Cell Mass Cell Fate Commitment Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Nucleic Acid Phosphodiester Bond Hydrolysis Microtubule-based Process Female Meiosis Sister Chromatid Cohesion Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion DNA Catabolic Process, Endonucleolytic Protein Stabilization Zonula Adherens Maintenance Cellular Response To Camptothecin Cellular Response To Hydroxyurea Cellular Macromolecule Catabolic Process Regulation Of Lymphocyte Activation Meiosis I Lymphocyte Activation Response To Camptothecin Negative Regulation Of Mitotic Recombination Microtubule Cytoskeleton Organization
Tagcloud ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus	altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2
Tagcloud (Difference) ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus	altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2
Tagcloud (Intersection) ?