RAD51C and SWSAP1

Number of citations of the paper that reports this interaction (PMID 21965664)
4

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RAD51C	SWSAP1
Gene Name		RAD51 paralog C	SWIM-type zinc finger 7 associated protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Rad51B-Rad51C-Rad51D-XRCC2 Complex Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm Holliday Junction Resolvase Complex	Nucleus Shu Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity	Single-stranded DNA Binding Protein Binding ATPase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Sister Chromatid Cohesion Female Meiosis Sister Chromatid Cohesion Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination Protein Stabilization
Pathways		Meiotic recombination Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Primary tooth development (time to first tooth eruption) ( 23704328) Testicular germ cell tumor ( 23666239 23666240)
Protein-Protein Interactions		6 interactors: APP RAD51 RAD51B RAD51D SWSAP1 XRCC3	7 interactors: A2M RAD51 RAD51B RAD51C RAD51D XRCC3 ZSWIM7
Entrez ID		5889	126074
HPRD ID		04143	08179
Ensembl ID		ENSG00000108384	ENSG00000173928
Uniprot IDs		O43502	Q6NVH7
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Reciprocal Meiotic Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Meiosis I Positive Regulation Of Mitotic Cell Cycle Cellular Response To Stress Meiotic Nuclear Division Response To Stress Meiotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Mitotic Recombination Positive Regulation Of Cell Cycle Reproduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle G2/M Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process Cellular Response To Stimulus Synaptic Growth At Neuromuscular Junction Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion Collateral Sprouting In Absence Of Injury Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Response To Camptothecin Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition DNA Recombinase Assembly Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Cycle Process Positive Regulation Of Spindle Checkpoint Axon Choice Point Recognition	Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination Reciprocal Meiotic Recombination DNA Repair Meiosis I Cellular Response To DNA Damage Stimulus DNA Metabolic Process Meiotic Nuclear Division Meiotic Cell Cycle Cellular Response To Stress Response To Stress Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Mitotic Recombination Positive Regulation Of Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Reproduction Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Cellular Response To Stimulus Regulation Of Mitotic Cell Cycle Blood Coagulation Hemostasis Regulation Of Cell Cycle Process DNA Catabolic Process, Endonucleolytic Nucleobase-containing Compound Metabolic Process Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Body Fluid Levels Cellular Nitrogen Compound Metabolic Process Wound Healing Female Meiosis Sister Chromatid Cohesion Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Negative Regulation Of Complement Activation, Lectin Pathway Strand Invasion Response To Stimulus DNA Catabolic Process Response To Wounding Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Nitrogen Compound Metabolic Process Response To Camptothecin DNA Recombinase Assembly
Tagcloud ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus
Tagcloud (Difference) ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus
Tagcloud (Intersection) ?