RAD51C and RAD51B

Number of citations of the paper that reports this interaction (PMID 11751636)
60

Data Source:
HPRD (two hybrid, in vivo)

		RAD51C	RAD51B
Gene Name		RAD51 paralog C	RAD51 paralog B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Rad51B-Rad51C-Rad51D-XRCC2 Complex Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm Holliday Junction Resolvase Complex	Nucleus Nucleoplasm Replication Fork Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity	Four-way Junction DNA Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Sister Chromatid Cohesion Female Meiosis Sister Chromatid Cohesion Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Reciprocal Meiotic Recombination Blood Coagulation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Pathways		Meiotic recombination Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Primary tooth development (time to first tooth eruption) ( 23704328) Testicular germ cell tumor ( 23666239 23666240)	Age-related macular degeneration ( 23455636) Breast cancer (male) ( 23001122) Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: APP RAD51 RAD51B RAD51D SWSAP1 XRCC3	9 interactors: FAM9B H1F0 HIST1H2BG HIST1H3A HIST2H4A RAD51C RAD51D SWSAP1 UBC
Entrez ID		5889	5890
HPRD ID		04143	04255
Ensembl ID		ENSG00000108384	ENSG00000182185
Uniprot IDs		O43502	O15315
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Reciprocal Meiotic Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Meiosis I Positive Regulation Of Mitotic Cell Cycle Cellular Response To Stress Meiotic Nuclear Division Response To Stress Meiotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Mitotic Recombination Positive Regulation Of Cell Cycle Reproduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle G2/M Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process Cellular Response To Stimulus Synaptic Growth At Neuromuscular Junction Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion Collateral Sprouting In Absence Of Injury Positive Regulation Of DNA Ligation Cellular Response To Camptothecin Response To Camptothecin Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition DNA Recombinase Assembly Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Cycle Process Positive Regulation Of Spindle Checkpoint Axon Choice Point Recognition	DNA Metabolic Process Nucleosome Assembly Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Chromosome Organization DNA Packaging DNA Conformation Change Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Double-strand Break Repair DNA Repair Cellular Macromolecular Complex Assembly DNA Recombination Chromatin Organization Chromatin Silencing Nucleobase-containing Compound Metabolic Process Reciprocal Meiotic Recombination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Organelle Organization Cellular Nitrogen Compound Metabolic Process DNA Methylation Response To Stress Protein Complex Assembly Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Telomere Maintenance DNA Modification DNA Catabolic Process, Endonucleolytic Gene Silencing Meiosis I Cell Cycle Female Meiosis Sister Chromatid Cohesion Strand Invasion DNA Catabolic Process Cellular Response To Stress Histone H4-K20 Demethylation Meiotic Nuclear Division Negative Regulation Of Megakaryocyte Differentiation Meiotic Sister Chromatid Cohesion Meiotic Cell Cycle Regulation Of Gene Expression, Epigenetic Cellular Component Assembly Cellular Macromolecule Catabolic Process
Tagcloud ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus	aetiology argues atlas billion clues coadaptation cohorts comprehensive confirms constitutes encompassing extends give insertions landscape map massively observe oncogene papillomavirus proved reads screen sequencing transcriptome tumour uncovering unprecedented viruses
Tagcloud (Difference) ?		alu bisulfite chorionic collaborating conceived departments developmentally epimutation epimutations imprinted infrequent interspersed ivm lep line1 lit1 meg mest nanog nespas newborns nr3c1 oct4 peg3 pluripotency pyrosequencing reproduction snrpn villus	aetiology argues atlas billion clues coadaptation cohorts comprehensive confirms constitutes encompassing extends give insertions landscape map massively observe oncogene papillomavirus proved reads screen sequencing transcriptome tumour uncovering unprecedented viruses
Tagcloud (Intersection) ?