BCCIP and CAPZB

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BCCIP	CAPZB
Description		BRCA2 and CDKN1A interacting protein	capping actin protein of muscle Z-line subunit beta
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Cytoplasm Cytosol Cytoskeleton Brush Border F-actin Capping Protein Complex Postsynaptic Density Actin Cytoskeleton Membrane Sarcomere Lamellipodium Cortical Cytoskeleton Asymmetric Synapse Extracellular Exosome WASH Complex Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Sperm Head-tail Coupling Apparatus
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity	Actin Binding Protein Binding Cadherin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair DNA Damage Response Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cell Morphogenesis Cell Projection Organization Lamellipodium Assembly Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Actin Filament Capping
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic RHOD GTPase cycle RHOF GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Appendicular lean mass ( 33097823) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)
Interacting Genes		28 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CPAP CSNK2B FCF1 GSK3A GSK3B H2BC15 HMGB2 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A ZNF138 ZNF19	10 interacting genes: BCCIP CDC42 CEBPA CFTR MRPL20 MTPN PTN RPP14 SIRPA VHL
Entrez ID		56647	832
HPRD ID		16542	11872
Ensembl ID		ENSG00000107949	ENSG00000077549
Uniprot IDs		Q9P287	A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs		7KYQ 7KYS 8EQB 8EXE 8EXF	8F8Q
Enriched GO Terms of Interacting Partners?		Nuclear Ubiquitin Ligase Complex Mitotic Recombination-dependent Replication Fork Processing Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Damage Checkpoint Cellular Response To Ionizing Radiation Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Oxygen-containing Compound Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of Glycogen (starch) Synthase Activity Protein-containing Complex Regulation Of Epithelial Cell Proliferation Regulation Of Cell-substrate Adhesion Negative Regulation Of Catabolic Process Regulation Of Proteolysis Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Cell Cycle Regulation Of Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell-substrate Adhesion Cellular Response To Interleukin-3 Response To Glycoside Regulation Of Protein Modification Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Response To Ionizing Radiation Regulation Of Protein Metabolic Process Response To Gamma Radiation Negative Regulation Of Proteolysis Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of TOR Signaling Cellular Response To Antibiotic Regulation Of Cell Migration Negative Regulation Of Catalytic Activity Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Organelle Organization Regulation Of Intracellular Signal Transduction Cellular Response To Radiation Apoptotic Signaling Pathway Regulation Of Cell Motility	Organelle Localization Mononuclear Cell Migration Positive Regulation Of Cell Division Apolipoprotein A-I Receptor Binding Macrophage Differentiation Response To Type II Interferon Endothelin Receptor Signaling Pathway Involved In Heart Process Leukocyte Migration Protein-containing Complex Cellular Response To Cytokine Stimulus Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Integrin-mediated Signaling Pathway Cellular Response To Type II Interferon Sterol Metabolic Process Cholesterol Metabolic Process CHOP-C/EBP Complex Cellular Response To Stress RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 White Fat Cell Proliferation Memory C/EBP Complex Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Positive Regulation Of Biomineral Tissue Development Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Dendrite Regeneration Ossification Involved In Bone Remodeling Protein Phosphatase Inhibitor Activity Endoribonuclease Complex Ribonuclease P Complex Kinase Regulator Activity Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Protein Binding Involved In Heterotypic Cell-cell Adhesion Cellular Response To Interleukin-12 Response To Interleukin-12
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?