BCCIP and RPL38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BCCIP	RPL38
Description		BRCA2 and CDKN1A interacting protein	ribosomal protein L38
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Cytoplasm Cytosol Ribosome Focal Adhesion Postsynaptic Density Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Eukaryotic 80S Initiation Complex Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair DNA Damage Response Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Skeletal System Development Ossification Cytoplasmic Translation Translation Regulation Of Translation Sensory Perception Of Sound Protein-RNA Complex Assembly 90S Preribosome Assembly Middle Ear Morphogenesis Axial Mesoderm Development
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Depression in smokers ( 30219690) Polymyositis ( 26362759)
Interacting Genes		28 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CPAP CSNK2B FCF1 GSK3A GSK3B H2BC15 HMGB2 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A ZNF138 ZNF19	5 interacting genes: AP2M1 BCCIP CHMP5 LILRB3 PTEN
Entrez ID		56647	6169
HPRD ID		16542	16048
Ensembl ID		ENSG00000107949	ENSG00000172809
Uniprot IDs		Q9P287	P63173
PDB IDs		7KYQ 7KYS 8EQB 8EXE 8EXF	4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6SXO 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7XNX 7XNY 8A3D 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8ONY 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9FPZ 9FQ0 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Nuclear Ubiquitin Ligase Complex Mitotic Recombination-dependent Replication Fork Processing Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Damage Checkpoint Cellular Response To Ionizing Radiation Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Oxygen-containing Compound Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of Glycogen (starch) Synthase Activity Protein-containing Complex Regulation Of Epithelial Cell Proliferation Regulation Of Cell-substrate Adhesion Negative Regulation Of Catabolic Process Regulation Of Proteolysis Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Cell Cycle Regulation Of Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell-substrate Adhesion Cellular Response To Interleukin-3 Response To Glycoside Regulation Of Protein Modification Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Response To Ionizing Radiation Regulation Of Protein Metabolic Process Response To Gamma Radiation Negative Regulation Of Proteolysis Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of TOR Signaling Cellular Response To Antibiotic Regulation Of Cell Migration Negative Regulation Of Catalytic Activity Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Organelle Organization Regulation Of Intracellular Signal Transduction Cellular Response To Radiation Apoptotic Signaling Pathway Regulation Of Cell Motility	Vesicle Budding From Membrane Membrane Organization Cytoplasmic Side Of Plasma Membrane Negative Regulation Of Synaptic Vesicle Clustering Spindle Assembly Plasma Membrane Organization Membrane Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Spindle Organization Central Nervous System Myelin Maintenance Organelle Assembly Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Kinase Regulator Activity Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Organelle Organization Positive Regulation Of Synaptic Vesicle Endocytosis Vesicle Organization Regulation Of Cellular Component Size Positive Regulation Of Synaptic Vesicle Recycling AP-2 Adaptor Complex Postsynaptic Neurotransmitter Receptor Internalization Clathrin Adaptor Complex Cellular Component Assembly Signal Sequence Binding Extrinsic Component Of Presynaptic Endocytic Zone Membrane Locomotor Rhythm Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Negative Regulation Of Cell Size Negative Regulation Of Cell Development Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Membraneless Organelle Assembly
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