BCCIP and HIST1H2BN

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BCCIP	HIST1H2BN
Gene Name		BRCA2 and CDKN1A interacting protein	histone cluster 1, H2bn
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex	Nucleosome Nucleus Nucleoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Regulator Activity Poly(A) RNA Binding	DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Cell Cycle Neuroendocrine Cell Differentiation	Chromatin Organization Nucleosome Assembly
Pathways			RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Chromatin organization HDACs deacetylate histones misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B FAM46A HIST1H2BN ITSN2 PTN RAD51 RPL23	2 interactors: BCCIP EWSR1
Entrez ID		56647	8341
HPRD ID		16542	11899
Ensembl ID		ENSG00000107949	ENSG00000233822
Uniprot IDs		B4DUS0 B4E318 Q9P287	Q99877 U3KQK0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Response To Ionizing Radiation Cell Cycle Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Ionizing Radiation Cellular Response To DNA Damage Stimulus Cell Aging Double-strand Break Repair Via Homologous Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Recombinational Repair Signal Transduction In Response To DNA Damage Negative Regulation Of MRNA 3'-end Processing Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Meiosis I DNA-dependent DNA Replication Signal Transduction By P53 Class Mediator Positive Regulation Of DNA Ligation Cellular Response To Camptothecin G2/M Transition Of Mitotic Cell Cycle Response To Camptothecin Response To UV Cellular Response To Radiation Cell Cycle Arrest DNA Recombinase Assembly Intestinal Epithelial Cell Maturation Double-strand Break Repair Cell Maturation DNA Repair Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Filopodium Assembly Xenobiotic Transport Protein-DNA Complex Assembly Meiotic Nuclear Division Negative Regulation Of Protein Export From Nucleus Cellular Macromolecular Complex Assembly Positive Regulation Of Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Protein K6-linked Ubiquitination Cellular Response To UV-B Replication Fork Protection Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Proliferation Adiponectin-activated Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Ribosomal Protein Import Into Nucleus Regulation Of Cell Proliferation Meiotic Cell Cycle	Neuroendocrine Cell Differentiation
Tagcloud ?		abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Difference) ?		abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated
Tagcloud (Intersection) ?