BCCIP and ZNF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BCCIP	ZNF19
Description		BRCA2 and CDKN1A interacting protein	zinc finger protein 19
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Mitotic Spindle Pole	Nucleus
	Molecular Function	RNA Binding Protein Binding Tubulin Binding Kinase Regulator Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization DNA Repair DNA Damage Response Mitotic Spindle Organization Microtubule Anchoring Neuroendocrine Cell Differentiation Mitotic Spindle Assembly	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494)	Intelligence (MTAG) ( 29326435)
Interacting Genes		28 interacting genes: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDC42 CDKN1A CPAP CSNK2B FCF1 GSK3A GSK3B H2BC15 HMGB2 ITSN2 MRPS9 OGT PDGFB PTN PTPRM RAD51 RALY RPL23 RPL38 SRC TENT5A ZNF138 ZNF19	22 interacting genes: AP1M1 ATPAF2 BCCIP BEX2 CARD9 CDR2L CIB3 CINP CSNK2B CTNNA3 FAM72D HOMER3 LMO1 LMO2 MAGOHB NDUFAB1 NUDT22 RFC5 SCNM1 SPANXN2 STX11 ZNF417
Entrez ID		56647	7567
HPRD ID		16542	01914
Ensembl ID		ENSG00000107949	ENSG00000157429
Uniprot IDs		Q9P287	P17023
PDB IDs		7KYQ 7KYS 8EQB 8EXE 8EXF
Enriched GO Terms of Interacting Partners?		Nuclear Ubiquitin Ligase Complex Mitotic Recombination-dependent Replication Fork Processing Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA Damage Checkpoint Cellular Response To Ionizing Radiation Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Oxygen-containing Compound Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of Glycogen (starch) Synthase Activity Protein-containing Complex Regulation Of Epithelial Cell Proliferation Regulation Of Cell-substrate Adhesion Negative Regulation Of Catabolic Process Regulation Of Proteolysis Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Cell Cycle Regulation Of Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell-substrate Adhesion Cellular Response To Interleukin-3 Response To Glycoside Regulation Of Protein Modification Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Response To Ionizing Radiation Regulation Of Protein Metabolic Process Response To Gamma Radiation Negative Regulation Of Proteolysis Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of TOR Signaling Cellular Response To Antibiotic Regulation Of Cell Migration Negative Regulation Of Catalytic Activity Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Organelle Organization Regulation Of Intracellular Signal Transduction Cellular Response To Radiation Apoptotic Signaling Pathway Regulation Of Cell Motility
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