BCCIP and RPL23

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, biochemical)
HPRD (two hybrid)

		BCCIP	RPL23
Gene Name		BRCA2 and CDKN1A interacting protein	ribosomal protein L23
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Regulator Activity Poly(A) RNA Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Cell Cycle Neuroendocrine Cell Differentiation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Ribosomal Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ABCB1 BARD1 BRCA2 CAPZB CCDC33 CDKN1A CSNK2B FAM46A HIST1H2BN ITSN2 PTN RAD51 RPL23	8 interactors: APP BCCIP CDC42 CLU DAPP1 EPS8L2 IPO5 RELA
Entrez ID		56647	9349
HPRD ID		16542	04716
Ensembl ID		ENSG00000107949
Uniprot IDs		B4DUS0 B4E318 Q9P287	P62829
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Cell Cycle Response To Ionizing Radiation Cell Cycle Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To Ionizing Radiation Cellular Response To DNA Damage Stimulus Cell Aging Double-strand Break Repair Via Homologous Recombination DNA Damage Response, Signal Transduction By P53 Class Mediator Recombinational Repair Signal Transduction In Response To DNA Damage Negative Regulation Of MRNA 3'-end Processing Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Meiosis I DNA-dependent DNA Replication Signal Transduction By P53 Class Mediator Positive Regulation Of DNA Ligation Cellular Response To Camptothecin G2/M Transition Of Mitotic Cell Cycle Response To Camptothecin Response To UV Cellular Response To Radiation Cell Cycle Arrest DNA Recombinase Assembly Intestinal Epithelial Cell Maturation Double-strand Break Repair Cell Maturation DNA Repair Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Filopodium Assembly Xenobiotic Transport Protein-DNA Complex Assembly Meiotic Nuclear Division Negative Regulation Of Protein Export From Nucleus Cellular Macromolecular Complex Assembly Positive Regulation Of Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Protein K6-linked Ubiquitination Cellular Response To UV-B Replication Fork Protection Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Proliferation Adiponectin-activated Signaling Pathway Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Ribosomal Protein Import Into Nucleus Regulation Of Cell Proliferation Meiotic Cell Cycle	Regulation Of Catalytic Activity Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response Positive Regulation Of Cellular Component Biogenesis Response To Stimulus Regulation Of Protein Catabolic Process Positive Regulation Of Neuron Death Platelet Degranulation Regulation Of Protein Phosphorylation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Blood Coagulation Hemostasis Regulation Of ERBB Signaling Pathway Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Acetaldehyde Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Synapse Structure Or Activity Hair Follicle Development Positive Regulation Of Protein Metabolic Process Hair Cycle Process Immune Response Response To Amino Acid Hair Cycle Regulation Of Phosphorylation Defense Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Schwann Cell Differentiation Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell Projection Assembly Regulation Of Body Fluid Levels Positive Regulation Of NF-kappaB Transcription Factor Activity Wound Healing Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Immune Response Submandibular Salivary Gland Formation Collateral Sprouting In Absence Of Injury Actin Filament Branching
Tagcloud ?		abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Difference) ?		abundantly albeit antagonizes fbp fbp1 fuse hepatocellular hypothesize impairing implication interacted interacts knockdown oncogene p21 p53 physically proapoptotic protein1 proto radiation restored stably suppresses tctp transactivation transactivator tumorigenesis undifferentiated	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Intersection) ?