RAB13 and RAB7A

Number of citations of the paper that reports this interaction (PubMedID 21795389)
37

Data Source:
BioGRID (pull down)

		RAB13	RAB7A
Description		RAB13, member RAS oncogene family	RAB7A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Cell-cell Junction Bicellular Tight Junction Synaptic Vesicle Membrane Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchoring Junction	Autophagosome Membrane Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Endosome Late Endosome Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Endosome Membrane Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Retromer Complex Cytoplasmic Vesicle Late Endosome Membrane Mitochondrial Membrane Melanosome Membrane Phagophore Assembly Site Membrane Phagocytic Vesicle Extracellular Exosome Alveolar Lamellar Body Bounding Membrane Of Organelle Presynaptic Endosome Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Small GTPase Binding Retromer Complex Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Kinase A Signaling Protein Transport Endosomal Transport Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Toll-like Receptor 4 Signaling Pathway Endothelial Cell Chemotaxis Trans-Golgi Network To Recycling Endosome Transport Localization Within Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier Protein Localization To Cell Leading Edge	Autophagosome Assembly Protein Targeting To Lysosome Lipid Metabolic Process Endocytosis Autophagy Epidermal Growth Factor Catabolic Process Endosome To Lysosome Transport Response To Bacterium Protein Transport Lipid Catabolic Process Viral Release From Host Cell Protein To Membrane Docking Synaptic Vesicle Recycling Via Endosome Retrograde Transport, Endosome To Golgi Early Endosome To Late Endosome Transport Bone Resorption Positive Regulation Of Protein Catabolic Process Positive Regulation Of Viral Process Establishment Of Vesicle Localization Protein Localization To Lysosome Lipophagy Phagosome Maturation Phagosome Acidification Phagosome-lysosome Fusion Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Vesicle-mediated Transport In Synapse Endosome To Plasma Membrane Protein Transport Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Negative Regulation Of Intralumenal Vesicle Formation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	MHC class II antigen presentation Neutrophil degranulation TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle Prevention of phagosomal-lysosomal fusion Suppression of autophagy
Drugs			Guanosine-5'-Diphosphate
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Body fat mass ( 28552196) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes		10 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1	24 interacting genes: CHM KRTAP10-3 KRTAP10-9 PPP2R1A PPP2R1B PRKN RAB13 RAB17 RAB22A RAB4A RAB4B RAB6A RABAC1 RABGGTB RILP RNF115 RNF167 SLC2A4 TP53 UCHL5 VPS11 VPS16 VPS18 VPS41
Entrez ID		5872	7879
HPRD ID		04053	03805
Ensembl ID		ENSG00000143545	ENSG00000075785
Uniprot IDs		A0A087WWB9 P51153 Q504R6	A0A158RFU6 P51149
PDB IDs			1T91 1YHN 3LAW 6IYB 6WCW 7F6J 8KB8 8ZQ3
Enriched GO Terms of Interacting Partners?		Endosome Neurotransmitter Receptor Transport Endosome To Plasma Membrane Protein Transport Endocytic Recycling Cytoplasmic Vesicle Regulation Of Long-term Neuronal Synaptic Plasticity Small GTPase Binding Vesicle-mediated Transport To The Plasma Membrane Vesicle-mediated Transport SMAD Binding Regulation Of Neuronal Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cilium Protein-containing Complex Localization Presynaptic Endosome Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Positive Regulation Of Extracellular Matrix Assembly Endothelial Cell Activation Neurotransmitter Receptor Transport To Postsynaptic Membrane Endosomal Transport Phagocytic Vesicle Membrane Docking Establishment Of Protein Localization To Postsynaptic Membrane Protein Transport Neurotransmitter Receptor Transport To Plasma Membrane Cell Projection Organization Endosome Membrane Vesicle-mediated Transport In Synapse Recycling Endosome Membrane Intracellular Transport Trans-Golgi Network Membrane I-SMAD Binding Myosin V Binding Establishment Of Protein Localization Golgi Apparatus Recycling Endosome Regulation Of Extracellular Matrix Assembly Endocytosis Positive Regulation Of Extracellular Matrix Organization Centriole Cardiac Epithelial To Mesenchymal Transition Cellular Localization Establishment Of Localization In Cell Activin Receptor Signaling Pathway Neuron Projection Development Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse	Vesicle-mediated Transport Intracellular Transport Endosomal Vesicle Fusion Cellular Localization Establishment Of Localization In Cell Insulin-responsive Compartment Protein Transport Endosome HOPS Complex Regulation Of SNARE Complex Assembly Establishment Of Protein Localization Intracellular Protein Transport Endosome To Lysosome Transport Vesicle Organization Lysosomal Transport Intracellular Protein Localization Cytoplasmic Vesicle CORVET Complex Clathrin-coated Vesicle Endosomal Transport Endosome Organization Late Endosome Endomembrane System Vacuolar Transport Golgi Vesicle Transport Vesicle Fusion Organelle Membrane Fusion Organelle Organization Organelle Fusion Recycling Endosome Membrane Fusion Late Endosome Membrane Endosome Membrane Cytosol Autophagy Rab-protein Geranylgeranyltransferase Complex Rab Geranylgeranyltransferase Activity Organelle Localization Meiotic Sister Chromatid Cohesion, Centromeric Membrane Organization Vesicle Tethering Complex GTPase Activity Early Endosome GTP Binding Protein Geranylgeranylation Lysosomal Membrane Presynapse Protein Prenylation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Meiotic Sister Chromatid Cohesion
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