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RAB2A and ICA1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
RAB2A
ICA1
Description
RAB2A, member RAS oncogene family
islet cell autoantigen 1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Autophagosome Membrane
Acrosomal Vesicle
Nucleus
Cytoplasm
Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Cytoplasmic Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Melanosome
Extracellular Exosome
Golgi Membrane
Cytoplasm
Golgi Apparatus
Cytosol
Endomembrane System
Membrane
Transport Vesicle Membrane
Secretory Granule Membrane
Synaptic Vesicle Membrane
Cytoplasmic Vesicle
Synapse
Molecular Function
Nucleotide Binding
GTPase Activity
G Protein Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
Metal Ion Binding
Protein Binding
Protein Domain Specific Binding
Membrane Curvature Sensor Activity
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Golgi Organization
Protein Transport
Vesicle-mediated Transport
Macroautophagy
Autophagosome-lysosome Fusion
Neurotransmitter Transport
Regulation Of Secretion
Membrane Bending
Pathways
Golgi Cisternae Pericentriolar Stack Reorganization
RAB geranylgeranylation
Drugs
Diseases
GWAS
Aspartate aminotransferase levels (
33547301
)
Autoimmune thyroid disease (
32581359
)
Estimated glomerular filtration rate (
31152163
)
Low density lipoprotein cholesterol levels (
32154731
)
Neutrophil count (
32888494
)
Systemic sclerosis (
31672989
)
Total cholesterol levels (
29083408
)
Cognitive function (
24684796
)
Intraocular pressure (
23836780
)
Metabolite levels (Pyroglutamine) (
23934736
)
Night sleep phenotypes (
27126917
)
Obesity-related traits (
23251661
)
Systemic lupus erythematosus (
28714469
)
Interacting Genes
29 interacting genes:
BLZF1
CBFB
CCDC125
CEBPA
CFL2
FAM114A1
FAM114A2
FRMD1
GAA
GAPDH
GARIN4
GARIN6
GDI2
GOLGA2
GORASP2
HES6
ICA1
MAPK6
MAPKAPK3
OTOS
PMAIP1
PRKCI
RBSN
RGS2
SGSM2
STAMBPL1
TBC1D25
TMEM70
TRIM7
9 interacting genes:
CCDC28A
EXOC5
ING5
MBD3
RAB2A
RAB2B
SHANK3
SNCA
TSC1
Entrez ID
5862
3382
HPRD ID
01539
00971
Ensembl ID
ENSG00000104388
ENSG00000003147
Uniprot IDs
P61019
A0A024RA29
Q05084
PDB IDs
1Z0A
Enriched GO Terms of Interacting Partners
?
Autophagosome Membrane
Response To Desipramine
Regulation Of Neuronal Synaptic Plasticity
Negative Regulation Of Norepinephrine Uptake
Phospholipase D Inhibitor Activity
Regulation Of Long-term Neuronal Synaptic Plasticity
Adult Behavior
Positive Regulation Of SNARE Complex Assembly
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Hsp70 Protein Binding
Synapse Organization
Memory T Cell Differentiation
Acrosomal Vesicle
Negative Regulation Of Serotonin Uptake
Positive Regulation Of Exocytosis
Adult Locomotory Behavior
Transporter Regulator Activity
Regulation Of Norepinephrine Uptake
Regulation Of Supramolecular Fiber Organization
Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone
Negative Regulation Of Autophagy
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Negative Regulation Of Chaperone-mediated Autophagy
Cell Junction Organization
Regulation Of Cell Size
TSC1-TSC2 Complex
Associative Learning
DNA Replication-dependent Chromatin Disassembly
Guanylate Kinase-associated Protein Clustering
Positive Regulation Of Synapse Structural Plasticity
Striatal Medium Spiny Neuron Differentiation
Golgi Organization
Vesicle-mediated Transport
Negative Regulation Of Dopamine Metabolic Process
Regulation Of Serotonin Uptake
Synaptic Receptor Adaptor Activity
Regulation Of Cytoskeleton Organization
Negative Regulation Of Thrombin-activated Receptor Signaling Pathway
Negative Regulation Of Catecholamine Metabolic Process
Positive Regulation Of Synaptic Transmission
ATPase Inhibitor Activity
Negative Regulation Of Cell Volume
AMPA Glutamate Receptor Clustering
NMDA Glutamate Receptor Clustering
Macroautophagy
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Supramolecular Fiber Organization
Negative Regulation Of Cytoskeleton Organization
Learning
Response To Bisphenol A
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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