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RAB2A and CBFB
Number of citations of the paper that reports this interaction (PubMedID
20195357
)
57
Data Source:
BioGRID
(pull down)
RAB2A
CBFB
Description
RAB2A, member RAS oncogene family
core-binding factor subunit beta
Image
GO Annotations
Cellular Component
Golgi Membrane
Autophagosome Membrane
Acrosomal Vesicle
Nucleus
Cytoplasm
Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Cytoplasmic Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Melanosome
Extracellular Exosome
Nucleus
Nucleoplasm
Membrane
Core-binding Factor Complex
Molecular Function
Nucleotide Binding
GTPase Activity
G Protein Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
Metal Ion Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
Sequence-specific DNA Binding
Biological Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Golgi Organization
Protein Transport
Vesicle-mediated Transport
Macroautophagy
Autophagosome-lysosome Fusion
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Ossification
Osteoblast Differentiation
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Lymphocyte Differentiation
Myeloid Cell Differentiation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Definitive Hemopoiesis
Pathways
Golgi Cisternae Pericentriolar Stack Reorganization
RAB geranylgeranylation
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Transcriptional regulation by RUNX2
Transcriptional regulation by RUNX2
RUNX1 regulates estrogen receptor mediated transcription
Regulation of RUNX1 Expression and Activity
RUNX1 regulates expression of components of tight junctions
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
RUNX1 regulates transcription of genes involved in BCR signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX1 regulates transcription of genes involved in interleukin signaling
RUNX1 regulates transcription of genes involved in WNT signaling
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
RUNX2 regulates osteoblast differentiation
RUNX2 regulates osteoblast differentiation
RUNX2 regulates chondrocyte maturation
RUNX2 regulates bone development
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in differentiation of myeloid cells
Regulation of RUNX3 expression and activity
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 regulates RUNX1-mediated transcription
RUNX3 regulates p14-ARF
Estrogen-dependent gene expression
Transcriptional regulation of granulopoiesis
Drugs
Diseases
GWAS
Aspartate aminotransferase levels (
33547301
)
Autoimmune thyroid disease (
32581359
)
Estimated glomerular filtration rate (
31152163
)
Low density lipoprotein cholesterol levels (
32154731
)
Neutrophil count (
32888494
)
Systemic sclerosis (
31672989
)
Total cholesterol levels (
29083408
)
Appendicular lean mass (
33097823
)
Mean corpuscular hemoglobin (
27863252
)
Interacting Genes
29 interacting genes:
BLZF1
CBFB
CCDC125
CEBPA
CFL2
FAM114A1
FAM114A2
FRMD1
GAA
GAPDH
GARIN4
GARIN6
GDI2
GOLGA2
GORASP2
HES6
ICA1
MAPK6
MAPKAPK3
OTOS
PMAIP1
PRKCI
RBSN
RGS2
SGSM2
STAMBPL1
TBC1D25
TMEM70
TRIM7
9 interacting genes:
CBFA2T2
CHGB
CHRM5
COPRS
RAB2A
RNF7
RUNX1
RUNX2
RUNX3
Entrez ID
5862
865
HPRD ID
01539
00418
Ensembl ID
ENSG00000104388
ENSG00000067955
Uniprot IDs
P61019
Q13951
PDB IDs
1Z0A
1CL3
1E50
1H9D
4N9F
6NIL
6P59
6VGD
6VGE
6VGG
8CX0
8CX1
8CX2
8E40
8FVI
8FVJ
8H0I
8J62
8SZK
Enriched GO Terms of Interacting Partners
?
Core-binding Factor Complex
Chondrocyte Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation
Peripheral Nervous System Neuron Development
Ossification
Regulation Of CD8-positive, Alpha-beta T Cell Activation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Hemopoiesis
Negative Regulation Of Alpha-beta T Cell Differentiation
Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation
Transcription Corepressor Binding
Negative Regulation Of Alpha-beta T Cell Activation
Negative Regulation Of T Cell Differentiation
Positive Regulation Of Alpha-beta T Cell Differentiation
Negative Regulation Of Lymphocyte Differentiation
Negative Regulation Of Cell Adhesion
Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Ligamentous Ossification
Neuron Differentiation
Stem Cell Proliferation
Positive Regulation Of Alpha-beta T Cell Activation
Regulation Of CD4-positive, Alpha-beta T Cell Activation
Osteoblast Fate Commitment
Negative Regulation Of Focal Adhesion Disassembly
Positive Regulation Of Cell Adhesion
Negative Regulation Of Hemopoiesis
Positive Regulation Of T Cell Differentiation
Regulation Of Alpha-beta T Cell Activation
Cardiac Muscle Tissue Regeneration
NEDD8 Ligase Activity
Positive Regulation Of Lymphocyte Differentiation
Negative Regulation Of T Cell Activation
G Protein-coupled Acetylcholine Receptor Activity
Regulation Of Phosphatidylinositol Dephosphorylation
NEDD8 Transferase Activity
Negative Regulation Of DNA-templated Transcription
Sequence-specific Double-stranded DNA Binding
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Leukocyte Cell-cell Adhesion
Phosphocreatine Biosynthetic Process
Negative Regulation Of Lymphocyte Activation
Neuron Development
Negative Regulation Of RNA Metabolic Process
Regulation Of Odontogenesis Of Dentin-containing Tooth
Cell Differentiation
DNA-binding Transcription Factor Binding
Response To Sodium Phosphate
DNA-binding Transcription Factor Activity
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