ICA1 and RAB2B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ICA1	RAB2B
Gene Name		islet cell autoantigen 1, 69kDa	RAB2B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Cell Junction Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Protein Domain Specific Binding	GTPase Activity GTP Binding GDP Binding
	Biological Process	Neurotransmitter Transport	Intracellular Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B	9 interactors: ADAMTSL4 APP BLZF1 FAM114A1 FAM71C GOLGA2 ICA1 SMAD1 SMAD4
Entrez ID		3382	84932
HPRD ID		00971	06312
Ensembl ID		ENSG00000003147	ENSG00000129472
Uniprot IDs		Q05084 Q96HG3	B4DUD4 Q6NZ33 Q8WUD1
PDB IDs			2A5J
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Ras Protein Signal Transduction Peptidyl-lysine Modification Methylation-dependent Chromatin Silencing Organelle Organization Protein Transport Establishment Of Protein Localization Intracellular Transport Histone Modification Protein Localization Establishment Of Localization In Cell Chromatin Modification Small GTPase Mediated Signal Transduction Chromatin Silencing	SMAD Protein Complex Assembly Regulation Of Binding BMP Signaling Pathway Embryonic Pattern Specification Growth Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Regulation Of Growth Synaptic Growth At Neuromuscular Junction Nephrogenic Mesenchyme Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Mesoderm Development Regulation Of Protein Binding Collateral Sprouting In Absence Of Injury Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Kidney Epithelium Development Cell Proliferation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Gastrulation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cell Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Endocardial Cell Differentiation Primary MiRNA Processing Axon Choice Point Recognition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Osteoblast Fate Commitment Positive Regulation Of Transcription From RNA Polymerase II Promoter Formation Of Anatomical Boundary Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Endothelial Cell Activation Neuron Remodeling Regulation Of Transforming Growth Factor Beta2 Production Developmental Growth Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Cell Fate Commitment Protein O-linked Fucosylation Kidney Development Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Tagcloud ?		6x10 7x10 aicda bank1 card8 ccl11 eotaxin fisher formations gc germinal ikbke il17a keratoconjunctivitis lacrimal minor norwegian pkn1 pss rheumatic salivary sicca sjogren snps suggestive suggestively swedish tank xerostomia	amplify annotated bv ccl5 cd80 chemokines cinnamomi cr cutoff cxcl10 cyclooxygenase grin2a ifi203 ifit1 il1alpha il6 imply inos lilrb3 lps microglia microglial nos2 periphery ramulus rsad2 supplemental table vpreb1
Tagcloud (Difference) ?		6x10 7x10 aicda bank1 card8 ccl11 eotaxin fisher formations gc germinal ikbke il17a keratoconjunctivitis lacrimal minor norwegian pkn1 pss rheumatic salivary sicca sjogren snps suggestive suggestively swedish tank xerostomia	amplify annotated bv ccl5 cd80 chemokines cinnamomi cr cutoff cxcl10 cyclooxygenase grin2a ifi203 ifit1 il1alpha il6 imply inos lilrb3 lps microglia microglial nos2 periphery ramulus rsad2 supplemental table vpreb1
Tagcloud (Intersection) ?