KMT2C and WDR5

  • Number of citations of the paper that reports this interaction (PMID 22266653)
  • 13
  • Data Source:
  • BioGRID (unspecified method, x-ray crystallography, unspecified method)

KMT2C

WDR5

Gene Name lysine (K)-specific methyltransferase 2C WD repeat domain 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 7 interactors: HIST1H3A HIST2H3C JUN MAPK14 SMARCB1 TSC22D1 WDR5 23 interactors: APP ATN1 CHD8 HIST1H1C HIST4H4 HSF2 IKBKG KMT2A KMT2B KMT2C MBIP MLLT1 POU5F1 PRMT5 PRNP RUSC1-AS1 SETD1A SETD1B SRPK2 SSX2IP TERF2IP TP53 ZXDC
Entrez ID 58508 11091
HPRD ID 06016 10614
Ensembl ID ENSG00000055609 ENSG00000196363
Uniprot IDs Q8NEZ4 P61964
PDB IDs 2YSM 2YUK 3UVL 4ERY 2CNX 2CO0 2G99 2G9A 2GNQ 2H13 2H14 2H68 2H6K 2H6N 2H6Q 2H9L 2H9M 2H9N 2H9P 2O9K 3EG6 3EMH 3MXX 3N0D 3N0E 3P4F 3PSL 3SMR 3UR4 3UVK 3UVL 3UVM 3UVN 3UVO 4A7J 4ERQ 4ERY 4ERZ 4ES0 4ESG 4EWR 4GM3 4GM8 4IA9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aacr  aggressive  ajuba  candidate  casp8  cdkn2a  clin  cscc  disfiguring  dominated  drive  driver  drivers  exome  fat1  foundation  hras  inactivating  lethal  links  mll3  mutational  mutsig  notch1  notch2  pard3  rasa1  res  suppressors 
acidic  allosterically  ash2l  box  compass  composed  concave  dpy30  erythroid  forming  heterodimer  interface  kmt2  lysine  methyltransferase  methyltransferases  mll1  mutational  rbbp5  referred  ryanodine  set1  spia  spry  stimulates  switch  trithorax  trxg  wrad 
Tagcloud (Difference) ?
aacr  aggressive  ajuba  candidate  casp8  cdkn2a  clin  cscc  disfiguring  dominated  drive  driver  drivers  exome  fat1  foundation  hras  inactivating  lethal  links  mll3  mutsig  notch1  notch2  pard3  rasa1  res  suppressors 
acidic  allosterically  ash2l  box  compass  composed  concave  dpy30  erythroid  forming  heterodimer  interface  kmt2  lysine  methyltransferase  methyltransferases  mll1  rbbp5  referred  ryanodine  set1  spia  spry  stimulates  switch  trithorax  trxg  wrad 
Tagcloud (Intersection) ?
mutational