KMT2C

Gene Name		lysine (K)-specific methyltransferase 2C
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Poly(A) RNA Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Intracellular Signal Transduction Histone H3-K4 Methylation
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: HIST1H3A HIST2H3C JUN MAPK14 SMARCB1 TSC22D1 WDR5
Entrez ID		58508
HPRD ID		06016
Ensembl ID		ENSG00000055609
Uniprot IDs		Q8NEZ4
PDB IDs		2YSM 2YUK 3UVL 4ERY
Enriched GO Terms of Interacting Partners?		Gene Expression Positive Regulation By Host Of Viral Transcription DNA Methylation On Cytosine Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Silencing At RDNA Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Wounding Interaction With Symbiont Nitrogen Compound Metabolic Process Chromatin Silencing Positive Regulation Of Viral Transcription Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway DNA Methylation TRIF-dependent Toll-like Receptor Signaling Pathway Transcription, DNA-templated MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Viral Transcription Methylation RNA Biosynthetic Process Blood Coagulation MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Viral Process Hemostasis Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Myeloid Cell Differentiation Toll-like Receptor 4 Signaling Pathway DNA Modification Positive Regulation Of Transcription, DNA-templated P38MAPK Cascade Cellular Response To Potassium Ion Starvation Regulation Of Metabolic Process Gene Silencing Toll-like Receptor Signaling Pathway Regulation Of Body Fluid Levels
Tagcloud ?		aacr aggressive ajuba candidate casp8 cdkn2a clin cscc disfiguring dominated drive driver drivers exome fat1 foundation hras inactivating lethal links mll3 mutational mutsig notch1 notch2 pard3 rasa1 res suppressors